4 Results for "

Dehydroevodiamine hydrochloride

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Dehydroevodiamine hydrochloride" in MCE Product Catalog:

3
Dehydroevodiamine hydrochloride
Dehydroevodiamine hydrochloride
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3 Cited Publications
Art. -Nr.: HY-N6029
CAS. Nr.: 111664-82-5
Category:  

Cardiovascular Disease Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants Disease Research Fields

Target:  

Cholinesterase (ChE) Beta-secretase Reactive Oxygen Species (ROS) Amyloid-β Endogenous Metabolite

Dehydroevodiamine hydrochloride is a blood-brain barrier-permeable, orally effective AChE and BACE1 inhibitor (IC50 = 40.96 μM). Dehydroevodiamine hydrochloride is isolated and extracted from Evodia rutaecarpa. Dehydroevodiamine hydrochloride attenuates neurotoxicity through multiple targets by inhibiting BACE1 to block Aβ production, inhibiting AChE activity, scavenging ROS, and suppressing calcium influx. Dehydroevodiamine hydrochloride can be used for research on Alzheimer's disease, cerebral ischemia, vascular dementia, and other cognitive disorder-related diseases .
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Dehydroevodiamine
Dehydroevodiamine
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Art. -Nr.: HY-N2106
CAS. Nr.: 67909-49-3
Category:  

Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Disease Research Fields Inflammation/Immunology Indole Alkaloids

Target:  

Cholinesterase (ChE) Beta-secretase Reactive Oxygen Species (ROS) Amyloid-β Endogenous Metabolite

Dehydroevodiamine is a blood-brain barrier-permeable, orally effective AChE and BACE1 inhibitor (IC50 = 40.96 μM). Dehydroevodiamine is isolated and extracted from Evodia rutaecarpa. Dehydroevodiamine attenuates neurotoxicity through multiple targets by inhibiting BACE1 to block Aβ production, inhibiting AChE activity, scavenging ROS, and suppressing calcium influx. Dehydroevodiamine can be used for research on Alzheimer's disease, cerebral ischemia, vascular dementia, and other cognitive disorder-related diseases .
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Dehydroevodiamine hydrochloride (Standard)
Dehydroevodiamine hydrochloride (Standard)
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Art. -Nr.: HY-N6029R
CAS. Nr.: 111664-82-5
Category:  

Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Quinoline Alkaloids Plants

Target:  

Reference Standards Cholinesterase (ChE) Beta-secretase Reactive Oxygen Species (ROS) Amyloid-β Endogenous Metabolite

Dehydroevodiamine hydrochloride Standard is the analytical standard of Dehydroevodiamine hydrochloride (HY-N6029). This product is intended for research and analytical applications. Dehydroevodiamine hydrochloride is a blood-brain barrier-permeable, orally effective AChE and BACE1 inhibitor (IC50 = 40.96 μM). Dehydroevodiamine hydrochloride is isolated and extracted from Evodia rutaecarpa. Dehydroevodiamine hydrochloride attenuates neurotoxicity through multiple targets by inhibiting BACE1 to block Aβ production, inhibiting AChE activity, scavenging ROS, and suppressing calcium influx. Dehydroevodiamine hydrochloride can be used for research on Alzheimer's disease, cerebral ischemia, vascular dementia, and other cognitive disorder-related diseases .
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Dehydroevodiamine (Standard)
Dehydroevodiamine (Standard)
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Art. -Nr.: HY-N2106R
CAS. Nr.: 67909-49-3
Category:  

Alkaloids Evodia rutaecarpa (Juss.) Benth. Rutaceae Plants Indole Alkaloids

Target:  

Reference Standards NF-κB COX PGE synthase NO Synthase

Dehydroevodiamine Standard is the analytical standard of Dehydroevodiamine (HY-N2106). This product is intended for research and analytical applications. Dehydroevodiamine is a blood-brain barrier-permeable, orally effective AChE and BACE1 inhibitor (IC50 = 40.96 μM). Dehydroevodiamine is isolated and extracted from Evodia rutaecarpa. Dehydroevodiamine attenuates neurotoxicity through multiple targets by inhibiting BACE1 to block Aβ production, inhibiting AChE activity, scavenging ROS, and suppressing calcium influx. Dehydroevodiamine can be used for research on Alzheimer's disease, cerebral ischemia, vascular dementia, and other cognitive disorder-related diseases .
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