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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
37 Results for "
ERBB3/HER3
" in MedChemExpress (MCE) Product Catalog:
Products (37)
37 Results for "ERBB3/HER3" in MCE Product Catalog:
3
3 Cited Publications
TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling .
2
1
1 Cited Publications
Cat. No.: HY-P70322
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SERBB3; HER3; P85-SERBB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ERBB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Recep
Species:
Human
Source:
HEK293
Cat. No.: HY-P99304
CAS No.: 1448327-63-6
Synonyms: Anti-Human ERBB3 Recombinant Antibody
Cat. No.: HY-B0426A
CAS No.: 140462-76-6
Synonyms: ALO4943A; KW4679
Target:
Research Areas:
Infection Neurological Disease Metabolic Disease Inflammation/Immunology
Olopatadine hydrochloride (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine hydrochloride exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine hydrochloride inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine hydrochloride also reduces the expression levels of CXCR3 on the surface of CD4 + and CD8 + T cells. Olopatadine hydrochloride inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine hydrochloride simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine hydrochloride can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis [3].
Cat. No.: HY-W062109
CAS No.: 113806-05-6
Target:
Research Areas:
Olopatadine (ALO4943A; KW4679) is an orally active histamine H1 receptor antagonist and mast cell stabilizer. Olopatadine exerts antiallergic effects by blocking histamine H1 receptor-mediated activities. Olopatadine inhibits exocytosis, chemokine release, F-actin polymerization, CXCL10-induced calcium influx, and T cell chemotactic activity. Olopatadine also reduces the expression levels of CXCR3 on the surface of CD4 + and CD8 + T cells. Olopatadine inhibits scratching behavior, improves dermatitis scores, and suppresses intraepidermal neurite outgrowth. Olopatadine simultaneously decreases the levels of inflammatory markers, growth factors, histamine, and specific IgE, while increasing the expression of ErbB3A/HER3A. Olopatadine can be used in research related to seasonal pollinosis, chronic rhinitis, urticaria, allergic conjunctivitis, alopecia areata, and atopic dermatitis [3].
Cat. No.: HY-P991245
Cat. No.: HY-P991241
Cat. No.: HY-P992128
CAS No.: 3059743-20-0
Rinumafusp alfa is a human monoclonal antibody targeting ERBB3/HER3. The corresponding isotype control is: Human IgG1 kappa, Isotype Control (HY-P99001).
Cat. No.: HY-W062109S
CAS No.: 1231979-85-3
Cat. No.: HY-P810613
Synonyms: ERBB3; HER3; Receptor tyrosine-protein kinase ERBB-3; Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3
Cat. No.: HY-P810612
Synonyms: ERBB3; HER3; Receptor tyrosine-protein kinase ERBB-3; Proto-oncogene-like protein c-ERBB-3; Tyrosine kinase-type cell surface receptor HER3
Cat. No.: HY-100848R
CAS No.: 1603845-32-4
Target:
Research Areas:
TX1-85-1 (Standard) is the analytical standard of TX1-85-1 (HY-100848). This product is intended for research and analytical applications. TX1-85-1 is an irreversible Her3 (ErbB3) inhibitor with an IC50 of 23 nM. TX1-85-1 is also the first selective Her3 ligand, which forms a covalent bond with Cys721 located in the ATP-binding site of Her3. TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling .
Cat. No.: HY-P72625
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SERBB3; HER3; P85-SERBB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ERBB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Recep
Species:
Human
Source:
HEK293
Cat. No.: HY-P74891
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SERBB3; HER3; P85-SERBB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ERBB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Recep
Species:
Rat
Source:
HEK293
Cat. No.: HY-P74892
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SERBB3; HER3; P85-SERBB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ERBB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Recep
Species:
Rat
Source:
HEK293
Cat. No.: HY-P76967
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ERBB3; Receptor Protein-Tyrosine Kinase; Prev. LCCS2; P45-SERBB3; HER3; P85-SERBB3; V-Erb-B2 Avian Erythroblastic Leukemia Viral Oncogene Homolog 3; ERBB-3 R31; Tyrosine Kinase-Type Cell Surface Receptor HER3; MDA-BF-1; Human Epidermal Growth Factor Recep
Species:
Rhesus Macaque
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
