2 Results for "

ERK1/2 inhibitor 11

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "ERK1/2 inhibitor 11" in MCE Product Catalog:

Cat. No.: HY-168171
Target:  

ERK Caspase Apoptosis

Research Areas:  

Cancer

ERK1/2 inhibitor 11 (compound L6) is a dual inhibitor of ERK1/2, lending to DSB accumulation and ERK1/2 expression degradation. ERK1/2 inhibitor 11 lowers the levels of BCL-2, and induces DNA damage by inhibiting PARP and ERK1/2. ERK1/2 inhibitor 11 activates caspase 3 to inducing apoptosis. [1].
loading...
    loading...
Cat. No.: HY-158098
CAS No.: 2157482-40-9
Target:  

FGFR

Research Areas:  

Metabolic Disease

FGFR1 inhibitor-11 (compound 5g) binds to FGFR1, inactivation of its downstream ERK1/2 and IκBα/NF-κB signaling inhibited RANKL-induced osteoclastogenesis. FGFR1 inhibitor-11 has oral bioactivity [1].
loading...
    loading...