32 Results for "

Furanocoumarin

" in MedChemExpress (MCE) Product Catalog:
Products (32)

32 Results for "Furanocoumarin" in MCE Product Catalog:

17
17 Cited Publications
Cat. No.: HY-30151
CAS No.: 298-81-7
Synonyms: 8-Methoxypsoralen; Xanthotoxin; 8-MOP
Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
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11
11 Cited Publications
Cat. No.: HY-N0763
CAS No.: 523-50-2
Synonyms: Isopsoralen
Angelicin is a furanocoumarin compound that functions as an inhibitor of NF-κB and MAPK signaling pathways, exhibiting anti-inflammatory, antiviral, and antitumor activities. It suppresses the lytic replication of γ-herpesviruses, such as MHV-68, early during viral infection, potentially inhibiting RTA gene expression (IC50=28.95 μM). Angelicin also mitigates inflammation by inhibiting the phosphorylation and nuclear translocation of NF-κB, and the phosphorylation of p38 and JNK. Furthermore, it induces apoptosis in neuroblastoma cells by downregulating anti-apoptotic proteins like Bcl-2, Bcl-xL, and Mcl-1, while activating caspase-9 and caspase-3.
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Cat. No.: HY-N1082
CAS No.: 82-57-5
Visnagin, an antioxidant furanocoumarin derivative, possess anti-inflammatory and analgesic properties. Visnagin has substantial potential to prevent Cerulein induced acute pancreatitis (AP). Visnagin possess promising vasodilator effects in vascular smooth muscles .
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Cat. No.: HY-N0747
CAS No.: 737-52-0
Oxypeucedanin is a furanocoumarin derivative found in Angelica dahurica. Oxypeucedanin is an orally active PI3K/AKT/NF-κB, MAPK, and ROS inhibitor. Oxypeucedanin induces cell cycle arrest and apoptosis. Oxypeucedanin inhibits hKv1.5 channel currents (IC50: 76 nM). Oxypeucedanin exhibits anticancer, anti-inflammatory, antioxidant and antiarrhythmic activities .
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Cat. No.: HY-N2272
CAS No.: 14348-22-2
Synonyms: Knidilin
Cnidilin (Knidilin) is isolated from the root of Angelica dahurica .
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Cat. No.: HY-N8354
CAS No.: 145414-76-2
Synonyms: 6′,7′-DHB
6',7'-Dihydroxybergamottin (6′,7′-DHB), a furanocoumarin, is a potent CYP3A4 inhibitor .
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Cat. No.: HY-N4053
CAS No.: 2880-49-1
Heraclenin, a natural furanocoumarin, significantly inhibits T cell receptor-mediated proliferation in human primary T cells in a concentration-dependent manner by targeting nuclear factor of activated T-cells (NFAT) .
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Cat. No.: HY-N0074A
CAS No.: 61046-59-1
(±)-Byakangelicol is a natural racemic furanocoumarin found in Magydaris panacifolia .
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Cat. No.: HY-N2262
CAS No.: 7437-55-0
8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM .
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Cat. No.: HY-N5110
CAS No.: 495-30-7
Synonyms: (-)-Marmesinin; Ammijin
Marmesinin ((-)-Marmesinin), a natural coumarin, is a biosynthetic precursor of psoralen and linear furanocoumarins. Marmesinin exhibits significant neuroprotective activities against glutamate-induced toxicity .
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Cat. No.: HY-U00265
CAS No.: 20073-24-9
Synonyms: 3-Carbethoxypsoralen; 3-Ethoxycarbonylpsoralen
Target:  

Bacterial

Research Areas:  

Infection

3-CPs is a monofunctional furanocoumarin and a photoprotective agent targeting Staphylococcus aureus DNA, possessesing anti-UVB lethal activity. 3-CPs competitively intercalates into DNA, forming exclusively 4',5'-furan-side mono-adducts upon UVB irradiation, and irreversibly inhibits the formation of cyclobutane pyrimidine dimers. 3-CPs prevents UVB-induced DNA damage by preferentially binding to strong (AT)n sites within the DNA, without inducing lethal interstrand DNA cross-links; the limited number of mono-adducts it induces can be efficiently repaired by bacteria. 3-CPs holds potential for use in the development of photoprotective formulations for skin diseases, as well as in studies investigating bacterial DNA photodamage repair mechanisms and the optimization of photochemotherapy safety .
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Cat. No.: HY-126754
CAS No.: 2607-56-9
Archangelicin is an inhibitor for cAMP-phosphodiesterase (cAMP-PDE) with IC50 >400 μM. Archangelicin inhibits nuclear factor of activated T cell (NFAT) with IC50 of 9 μM. Archangelicin exhibits antitumor and anti-inflammatory .
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Cat. No.: HY-N16528
CAS No.: 23517-02-4
(-)-Byakangelicin (Compound 9) is a furanocoumarin compound found in the peels of Citrus limon. (-)-Byakangelicin has antimutagenic activity for Trp-P-1 and PhIP and can be used for the research of cancer .
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Cat. No.: HY-W777749
CAS No.: 1246819-63-5
Synonyms: 8-Methoxypsoralen-13C,d3; Xanthotoxin-13C,d3; 8-MOP-13C,d3
Methoxsalen- 13C,d3 (8-Methoxypsoralen- 13C,d3) is the deuterium and 13C-labeled Methoxsalen (HY-30151). Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
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Cat. No.: HY-N9535A
CAS No.: 89560-97-4
(R)-tert-OMe-byakangelicin is a kind of furanocoumarin, which has inhibitory activity to liver drug metabolizing enzyme (DME) activity. (R)-tert-OMe-byakangelicin can be isolated from immature fruits of Angelica sinensis .
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Cat. No.: HY-N9354A
CAS No.: 125517-45-5
(+)-Saxalin is a furanocoumarin that can be found in Harbouria trachypleura .
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Cat. No.: HY-N2176A
CAS No.: 13710-70-8
(±)-Marmesin is a good precursor of the linear furanocoumarins. (±)-Marmesin derivatives have high degree of acetylcholinesterase inhibitory property .
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Cat. No.: HY-30151R
CAS No.: 298-81-7
Synonyms: 8-Methoxypsoralen (Standard); Xanthotoxin (Standard); 8-MOP (Standard)
Methoxsalen (Standard) is the analytical standard of Methoxsalen. This product is intended for research and analytical applications. Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
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Cat. No.: HY-N2262R
CAS No.: 7437-55-0
8-Geranyloxypsoralen (Standard) is the analytical standard of 8-Geranyloxypsoralen. This product is intended for research and analytical applications. 8-Geranyloxypsoralen is a furanocoumarin isolated from grapefruit, acts as a potent inhibitor of P450 3A4 (CYP3A4) with an IC50 of 3.93 μM .
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