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- Chrysanthemum × morifolium (Ramat.) Hemsl.
Chrysanthemum × morifolium (Ramat.) Hemsl.
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Chrysanthemum × morifolium (Ramat.) Hemsl. (43)
- Formula: C16H14O5
- Molecular Weight: 286.28
Oxypeucedanin is a furanocoumarin derivative found in Angelica dahurica. Oxypeucedanin is an orally active PI3K/AKT/NF-κB, MAPK, and ROS inhibitor. Oxypeucedanin induces cell cycle arrest and apoptosis. Oxypeucedanin inhibits hKv1.5 channel currents (IC50: 76 nM). Oxypeucedanin exhibits anticancer, anti-inflammatory, antioxidant and antiarrhythmic activities.
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- Formula: C17H24O2
- Molecular Weight: 260.37
Falcarindiol, an orally active polyacetylenic oxylipin, activates PPARγ and increases the expression of the cholesterol transporter ABCA1 in cells. Falcarindiol induces apoptosis and autophagy. Falcarindiol has anti-inflammatory, antifungal, anticancer and antidiabetic properties. Falcarindiol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- Formula: C16H14O5
- Molecular Weight: 286.28
Oxyimperatorin ((±)-Heraclenin) is a coumarin isolated from Angelica dahurica.
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- Formula: C21H22O7
- Molecular Weight: 386.40
(±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases.
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- Formula: C11H11N
- Molecular Weight: 157.22
2,6-Dimethylquinoline, a nature constituent from the roots of Peucedantu praeruptorum, is a CYP1A2 inhibitor with an IC50 of 3.3 µM. 2,6-Dimethylquinoline also inhibits CYP2B6 activity with an IC50 of 480 µM.
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- Formula: C21H22O7
- Molecular Weight: 386.40
(±)-Praeruptorin A (Standard) is the analytical standard of (±)-Praeruptorin A (HY-N0081). This product is intended for research and analytical applications. (±)-Praeruptorin A, a coumarin compound, is the main bioactive component in Peucedani Radix. As a calcium channel blocker, (±)-Praeruptorin A exhibits great antihypertensive effects. In addition, (±)-Praeruptorin A also has the effects of relaxing vascular smooth muscle, inhibiting airway inflammation and airway hyperresponsiveness. (±)-Praeruptorin A can be used for the research of allergic asthma, hypertension and other diseases.
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- Formula: C17H16O5
- Molecular Weight: 300.31
Cnidilin (Knidilin) is isolated from the root of Angelica dahurica.
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- Formula: C14H14O4
- Molecular Weight: 246.26
Nodakenetin is an orally active Wnt/β-catenin pathway activator. Nodakenetin reduces the level of DKK1, and upregulates c-Myc, cyclin D1 and survivin. Nodakenetin induces osteoprogenitor cell differentiation, upregulates bone formation biomarkers and prevents bone microstructure degeneration. Nodakenetin induces irritant skin reactions. Nodakenetin improves bone microstructure and histomorphometric parameters in osteoporotic mouse models. Nodakenetin can be used for osteoporosis-related research.
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- Formula: C24H28O7
- Molecular Weight: 428.47
Praeruptorin C is a main bioactive constituent of Peucedanum praeruptorum (also known as Bai-Hua Qian Hu). Praeruptorin C is a calcium antagonist with pD2′ value of 5.7.
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- Formula: C18H16O7
- Molecular Weight: 344.32
Tricetin 3',4',5'-trimethyl ether (5,7-Dihydroxy-3',4',5'-trimethoxyflavone) is a flavone glucoside, that can be isolated the flowers of Chrysanthemum sinensea. Tricetin 3',4',5'-trimethyl ether displays xanthine oxidase competitive-type inhibitory activity, with an IC50 of 0.51 μM and a Ki of 0.37 μM.
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- Formula: C22H24O7
- Molecular Weight: 400.42
Qianhucoumarin J (Compound 2) is a khellactone-derived coumarin (3'(S)-angeloyloxy-4'(S)-propionyloxy-3',4'-dihydroseselin) that can be found in the roots of Peucedanum praeruptorum Dunn.
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- Formula: C25H32O14
- Molecular Weight: 556.51
Praeroside VI (Compound 2) is a coumarin glycoside found in the roots of Peucedanum praeruptorum Dunn.
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- Formula: C27H28O12
- Molecular Weight: 544.50
4,5-O-Dicaffeoylquinic acid ethyl ester is an ABTS free radical scavenger with an IC50 of 5.95 μM. 4,5-O-Dicaffeoylquinic acid ethyl ester shows no antibacterial activity against Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. 4,5-O-Dicaffeoylquinic acid ethyl ester can be used in liver injury protection studies.
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- Formula: C24H30O7
- Molecular Weight: 430.49
Praeruptorin H is a natural product that can be found in white flower peucedanum.
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- Formula: C23H26O7
- Molecular Weight: 414.45
4'-O-Isobutyroylpeguangxienin is a natural coumarin.
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- Formula: C16H14O5
- Molecular Weight: 286.28
Oxypeucedanin (Standard) is a furanocoumarin derivative found in Angelica dahurica. Oxypeucedanin (Standard) is an orally active PI3K/AKT/NF-κB, MAPK, and ROS inhibitor. Oxypeucedanin (Standard) induces cell cycle arrest and apoptosis. Oxypeucedanin (Standard) inhibits hKv1.5 channel currents (IC50: 76 nM). Oxypeucedanin (Standard) exhibits anticancer, anti-inflammatory, antioxidant and antiarrhythmic activities.
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