4 Results for "

Fusarium fujikuroi

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Fusarium fujikuroi" in MCE Product Catalog:

Fumonisin B2
Fumonisin B2
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Art. -Nr.: HY-N6723
CAS. Nr.: 116355-84-1
Category:  

Infection Human Gut Microbiota Metabolites Microorganisms Antibiotics Disease Research Antibacterial Endogenous metabolite Disease Research Fields Other Antibiotics

Target:  

Ceramidase Acyltransferase

Fumonisin B2 is a selective ceramide synthase inhibitor and carcinogenic mycotoxin with toxicity comparable to that of Fumonisin B1 (HY-N6719). Fumonisin B2 inhibits de novo sphingolipid biosynthesis by blocking the amide bond formation between fatty acids and dihydrosphingosine, which leads to a massive intracellular accumulation of free dihydrosphingosine, altered sphingosine levels, subsequent inhibition of cell proliferation, and induction of cell death. Fumonisin B2 is used to investigate the pathogenesis of diseases associated with Fusarium verticillioides contamination, including equine leukoencephalomalacia, porcine pulmonary edema syndrome, human esophageal cancer, and rat hepatocellular carcinoma .
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WML-01
WML-01
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Art. -Nr.: HY-178717
CAS. Nr.: 3057478-36-8
Target:  

Fungal

Forschungsgebiete:  

Infection

WML-01 is a fungicide with EC50s of 0.079, 0.72 and 2.02 μg/mL against F. graminearum, F. fujikuroi and S. sclerotiorum. WML-01 disrupts the cell membrane of F. graminearum and induces deposition of lipid droplets. WML-01 inhibits Deoxynivalenol (DON) (HY-N6684) biosynthesis with no cross-resistance and strongly suppresses ribosomal subunit assembly, impairing protein synthesis. WML-01 effectively controls the fusarium head blight (FHB) epidemic .
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Gibepyrone D
Gibepyrone D
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Art. -Nr.: HY-N15498
CAS. Nr.: 146446-08-4
Category:  

Microorganisms Ketones, Aldehydes, Acids

Target:  

Insecticide

Gibepyrone D is an α-pyrone compound found in Gibberella fujikuroi and the endophytic fungus Fusarium oxysporum 162. Gibepyrone D exhibits significant lethal activity against nematodes with an LC50 value of 134 μg/mL (72 h) against the J2 larvae of Meloidogyne incognita. Gibepyrone D is promising for research of nematicides .
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Myosin I-IN-1
Myosin I-IN-1
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Art. -Nr.: HY-189346
Target:  

Myosin Fungal

Forschungsgebiete:  

Infection

Myosin I-IN-1 is an Antifungal agent and Myosin I inhibitor with a Kd of 0.14 μM for FgMyoI. Myosin I-IN-1 inhibits mycelial growth, sporulation, spore germination, and Deoxynivalenol (HY-N6684) biosynthesis. Myosin I-IN-1 disrupts cell wall and cell membrane integrity and induces hyphal morphological changes. Myosin I-IN-1 exhibits broad-spectrum antifungal activity against plant pathogenic fungi. Myosin I-IN-1 shows protective efficacy against Fusarium head blight in wheat and maize. Myosin I-IN-1 can be used for research on Fusarium head blight .
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