2. Search Result
Search Result
Pathways Recommended: GPCR/G Protein
Results for "

G 1

" in MedChemExpress (MCE) Product Catalog:

733

Inhibitors & Agonists

15

Biochemical Assay Reagents

19

Peptides

51

Inhibitory Antibodies

106

Natural
Products

62

Recombinant Proteins

18

Isotope-Labeled Compounds

48

Antibodies

4

Click Chemistry

20

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N1150
    Thymidine
    20+ Cited Publications

    DThyd; NSC 21548

    		 DNA/RNA Synthesis Endogenous Metabolite Orthopoxvirus Cancer
    Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication .
    Thymidine
  • HY-107216
    G-1
    25+ Cited Publications

    		 Estrogen Receptor/ERR Cancer
    G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM.
    G-1
  • HY-13650
    Indisulam
    10+ Cited Publications

    E 7070

    		 Molecular Glues Carbonic Anhydrase Cancer
    Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E. Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15 .
    Indisulam
  • HY-P99367
    Ifinatamab

    DS-7300a Antibody; MABX-9001A Antibody

    		 CD276/B7-H3 Inflammation/Immunology Cancer
    Ifinatamab is monoclonal immunoglobulin G1-kappa with anti-human B7 homolog 3 protein (Human B7-H3). Ifinatamab is a glycoforme α immunomodulateur .
    Ifinatamab
  • HY-101467
    Trilaciclib
    1 Publications Verification

    G1T28

    		 CDK Cancer
    Trilaciclib (G1T28) is an orally active CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. . Trilaciclib can effectively inhibit tumor cell proliferation and reduce the hematological toxicity caused by chemotherapy. Trilaciclib attenuates apoptosis and myelosuppression induced by 5FU (HY-90006) chemotherapy .
    Trilaciclib
  • HY-112272
    Lerociclib
    2 Publications Verification

    G1T38

    		 CDK Cancer
    Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
    Lerociclib
  • HY-13768
    Topotecan
    35+ Cited Publications

    SKF 104864A; NSC 609669

    		 Topoisomerase Autophagy Apoptosis Cancer
    Topotecan (SKF 104864A; NSC 609669) is an orally active and potent Topoisomerase I inhibitor. Topotecan induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan shows anticancer activity .
    Topotecan
  • HY-13680
    Meisoindigo
    2 Publications Verification

    Dian III; N-Methylisoindigotin; Natura-α

    		 Apoptosis Cancer
    Meisoindigo (Dian III), a derivative of Indirubin (HY-N0117), halts the cell cycle at the G0/G1 phase and induces apoptosis in primary acute myeloid leukemia (AML) cells. Meisoindigo exhibits high antitumor activity .
    Meisoindigo
  • HY-N3521
    Platycoside G1

    Deapi-platycoside E

    		 Others Others
    Platycoside G1, a natural product found in Platycodon grandiflorum, is a triterpenoid saponin. Platycoside G1 has potent antioxidant activities .
    Platycoside G1
  • HY-101467A
    Trilaciclib hydrochloride
    1 Publications Verification

    G1T28 hydrochloride

    		 CDK Cancer
    Trilaciclib (G1T28) hydrochloride is an orally active CDK4/6 inhibitor with IC50 values of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride can effectively inhibit tumor cell proliferation and reduce the hematological toxicity caused by chemotherapy. Trilaciclib hydrochloride attenuates apoptosis and myelosuppression induced by 5FU (HY-90006) chemotherapy .
    Trilaciclib hydrochloride
  • HY-120897
    NS-3-008 hydrochloride

    		Bcl-2 Family Apoptosis Inflammation/Immunology
    NS-3-008 hydrochloride is an orally active transcriptional inhibitor of G0/G1 switch 2 (G0s2) with an IC50 of 2.25 μM. NS-3-008 hydrochloride can be used for chronic kidney disease .
    NS-3-008 hydrochloride
  • HY-113638
    CVT-11127

    GS-456332

    		 Stearoyl-CoA Desaturase (SCD) Apoptosis Cancer
    CVT-11127 is a potent SCD inhibitor. CVT-11127 induces apoposis and arrests the cell cycle at the G1/S phase. CVT-11127 has the potential for the research of lung cancer .
    CVT-11127
  • HY-112197
    PKG drug G1
    2 Publications Verification

    		 PKG Cardiovascular Disease
    PKG agent G1 targets C42 of PKG Iα. PKG agent G1 can couple to vasodilation and blood pressure lowering by a C42 PKG Iα-independent mechanism.
    PKG drug G1
  • HY-137449
    Rintodestrant

    G1T48

    		 Estrogen Receptor/ERR CDK Cancer
    Rintodestrant (G1T48) is an orally active, non-steroidal and selective estrogen receptor degrader. Rintodestrant (G1T48) is also a CDK4/6 inhibitor .
    Rintodestrant
  • HY-112272A
    Lerociclib dihydrochloride
    2 Publications Verification

    G1T38 dihydrochloride

    		 CDK Cancer
    Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively.
    Lerociclib dihydrochloride
  • HY-P991033
    Tovecimig

    CTX-009

    		 VEGFR Inflammation/Immunology
    HY-P991033 is an VEGFA/DLL4-targeting G1-scFvlh_L-κ type bispecific antibody .
    Tovecimig
  • HY-169474
    Starburst 1st generation (13.93% w/w in water)

    PAMAM G1.0

    		 Biochemical Assay Reagents Cancer
    Starburst 1st Generation (PAMAM G1.0) is a Polyamidoamine (HY-164657; PAMAM) dendrimer with amine termini that has been used as a drug delivery system in vitro. Starburst 1st Generation conjugated to di-n-dodecylamine and encapsulating 5-Fluorouracil (HY-90006) increase the solubility of 5-Fluorouracil and are cytotoxic to AGS gastric adenocarcinoma cells .
    Starburst 1st generation (13.93% w/w in water)
  • HY-W127501
    Prostaglandin G1

    		Biochemical Assay Reagents Others
    Prostaglandin G1 is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Prostaglandin G1
  • HY-P990048
    Muzastotug

    ADG126

    		 CTLA-4 Cancer
    Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic .
    Muzastotug
  • HY-169932
    APOL1-IN-2

    		Apolipoprotein Infection
    APOL1-IN-2 (Compound 467) is the inhibitor for Apolipoprotein 1 (APOL1). APOL1-IN-2 reduces the APOL1 G2/G1 induced cell death in HEK293 with EC50 of 4.74 nM and 14.3 nM. APOL1-IN-2 reduces the APOL1 G2/G1/G0 induced death of trypanosomes with EC50 of 2.24, 6.03 and 3.72 nM, respectively .
    APOL1-IN-2
  • HY-RS04281
    EIF4G1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    EIF4G1 Human Pre-designed siRNA Set A contains three designed siRNAs for EIF4G1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    EIF4G1 Human Pre-designed siRNA Set A
    EIF4G1 Human Pre-designed siRNA Set A
  • HY-P99560
    Tadocizumab

    C4G1; YM-337

    		 Integrin Cardiovascular Disease
    Tadocizumab (C4G1; YM-337) is a humanized monoclonal antibody tageting integrin αIIbβ3. Tadocizumab has antiplatelet and antithrombotic effects, and can be used for cardiovascular disease research .
    Tadocizumab
  • HY-P990079
    Renvistobart

    BMS-986207; ONO-4686

    		 CD28 Inflammation/Immunology
    Renvistobart is an immunoglobulin G1-κ, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, VSIG9, VSTM3)] Homo sapiens monoclonal antibody .
    Renvistobart
  • HY-168620
    CDK6-IN-1

    		CDK Cancer
    CDK6-IN-1 (compound 4i) is a CDK6 inhibitor. CDK6-IN-1 inhibits cell growth and induces cell cycle arrest at G1-phase .
    CDK6-IN-1
  • HY-P99698
    Lesabelimab

    LDP

    		 PD-1/PD-L1 Inflammation/Immunology Cancer
    Lesabelimab (LDP) is an immunoglobulin G1-kappa anti-CD274 monoclonal antibody. CD274 is an immune checkpoint ligand, represses antitumour immunity through the interaction with PDCD1 receptor .
    Lesabelimab
  • HY-158473
    FA2[3]G1 & FA2[6]G1 glycan (G1F)

    FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide

    		 Biochemical Assay Reagents Others
    FA2[3]G1 & FA2[6]G1 glycan (G1F) (FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    FA2[3]G1 & FA2[6]G1 glycan (G1F)
  • HY-N14079
    Monamycin G1

    		Antibiotic Bacterial Infection
    Monamycin G1 is an ester peptide antibiotic. Monamycin G1 has activity against Gram-positive bacteria .
    Monamycin G1
  • HY-N14184
    Luminacin G1

    		Adrenergic Receptor Cardiovascular Disease
    Luminacin G1 has a strong inhibitory effect on capillary formation (IC50 is less than 0.1 μg/mL) .
    Luminacin G1
  • HY-107216R
    G-1 (Standard)

    		Reference Standards Estrogen Receptor/ERR Cancer
    G-1 (Standard) is the analytical standard of G-1 (HY-107216). This product is intended for research and analytical applications. G-1 is a nonsteroidal, high-affinity and selective agonist of GPR30 with a Ki of 11 nM.
    G-1 (Standard)
  • HY-W582827
    RuPhos Pd G1 methyl t-butyl ether adduct (MTBE)

    		Biochemical Assay Reagents Endogenous Metabolite
    RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) is a highly efficient catalyst with excellent cross-coupling activity. RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) is widely used in organic synthesis and can be used to promote various reactions to build complex molecular structures. RuPhos Pd G1 methyl t-butyl ether adduct (MTBE) has good adaptability to temperature and reaction conditions, which enables it to exhibit excellent catalytic performance in different reaction systems.
    RuPhos Pd G1 methyl t-butyl ether adduct (MTBE)
  • HY-P990020
    Eglatoprutug

    FSI-174

    		 c-Kit Others
    Eglatoprutug is an humanized immunoglobulin G1-kappa, anti-c-Kit monoclonal antibody .
    Eglatoprutug
  • HY-124261
    Sampangine

    		Apoptosis Cancer
    Sampangine is an alkaloid that induces apoptosis by inducing cell cycle arrest in the G0/G1 phase. Sampangine can inhibit the biosynthesis of heme .
    Sampangine
  • HY-P99886
    Pexelizumab

    h5G1. 1-SC

    		 Complement System Apoptosis Cardiovascular Disease Neurological Disease
    Pexelizumab (h5G1. 1-SC) is a humanized scFv monoclonal antibody directed against the C5 complement component. Pexelizumab inhibits apoptosis and leukocyte infiltration. Pexelizumab can be used for the research of cerebral IR injury and myocardial infarction .
    Pexelizumab
  • HY-147407
    Imbotolimod

    		EGFR Cancer
    Imbotolimod, immunoglobulin G1-kappa, is a humanized monoclonal antibody with anti-ERBB2 and antineoplastic activity. Imbotolimod is a derivative of telratolimod .
    Imbotolimod
  • HY-E70678
    CDK3/CycE1 Recombinant Human Active Protein Kinase

    		CDK Cancer
    CDK3 is a major player driving retinoblastoma (Rb) phosphorylation during the G0/G1 transition and in the early G1 phase of the cell cycle. CDK3 interacts with various transcription factors involved in cell proliferation, differentiation, and transformation driven by the EGFR/Ras signaling pathway. CDK3/CycE1 Recombinant Human Active Protein Kinase is an ortholog of CDK3 .
    CDK3/CycE1 Recombinant Human Active Protein Kinase
  • HY-135217
    Apiole

    		Apoptosis Cancer
    Apiole is an anti-tumor agent that induces apoptosis and inhibits human colon cancer cells by inducing G0/G1 cell cycle arrest. Apiole also significantly inhibited colon tumor development in an in vivo mouse xenograft model .
    Apiole
  • HY-144394
    Antitumor agent-45

    		Apoptosis c-Met/HGFR Cancer
    Antitumor agent-45 (Compound 21) could induce and stimulate A549 cells apoptosis in G0/G1 and G2/M phase. Antitumor agent-45 (Compound 21) inhibits c-Met expression to regulate the growth of tumor cells .
    Antitumor agent-45
  • HY-P991135
    Enzelkitug

    RO-7502175; RG-6411

    		 CCR Cancer
    Enzelkitug is a humanized immunoglobulin G1-κ monoclonal antibody targeting the human C-C motif chemokine receptor 8 (CCR8). Enzelkitug is promising for research of various solid tumors and hematological malignancies .
    Enzelkitug
  • HY-N2298
    Camellianin A

    		Apoptosis Cancer
    Camellianin A, the main flavonoid in A. nitida leaves, displays anticancer activity and angiotensin converting enzyme (ACE)-inhibitory activity. Camellianin A inhibits the proliferation of the human Hep G2 and MCF-7 cell lines and induces the significant increase of the G0/G1 cell population .
    Camellianin A
  • HY-13650R
    Indisulam (Standard)

    E 7070 (Standard)

    		 Molecular Glues Carbonic Anhydrase Reference Standards Cancer
    Indisulam (Standard) is the analytical standard of Indisulam. This product is intended for research and analytical applications. Indisulam (E 7070) is a carbonic anhydrase inhibitor with anticancer activity. Indisulam (E 7070) is a sulfonamide agent that targets the G1 phase of the cell cycle. Indisulam (E 7070) causes a blockade in the G1/S transition through inhibition of the activation of both CDK2 and cyclin E. Indisulam (E 7070) targets splicing by inducing RBM39 degradation via recruitment to DCAF15 .
    Indisulam (Standard)
  • HY-144733
    ERα antagonist 1

    		Estrogen Receptor/ERR Apoptosis Cancer
    ERα antagonist 1 (Compound 19d) is a potent, selective, covalent estrogen receptor α (ERα) antagonist. ERα antagonist 1 induces apoptosis and cell cycle G0/G1 phase arrest in MCF-7 cells .
    ERα antagonist 1
  • HY-N16567
    Acrofolione A

    		Apoptosis Caspase PARP Survivin Cancer
    Acrofolione A is an acetophenone dimer isolated from Acronychia pendunculata with anticancer effects. Acrofolione A induces G0/G1 phase cell cycle arrest and apoptosis in human NALM-6 pre-B cell leukaemia cells. Acrofolione A can be used for leukaemia research .
    Acrofolione A
  • HY-158480
    FA2[3]G1 & FA2[6]G1 glycan (G1F), procainamide labelled

    FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide, procainamide labelled

    		 Biochemical Assay Reagents Others
    FA2[3]G1 & FA2[6]G1 glycan (G1F), procainamide labelled (FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide, procainamide labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    FA2[3]G1 & FA2[6]G1 glycan (G1F), procainamide labelled
  • HY-158481
    FA2[3]G1 & FA2[6]G1 glycan (G1F), 2-AA labelled

    FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide, 2-AA labelled

    		 Biochemical Assay Reagents Others
    FA2[3]G1 & FA2[6]G1 glycan (G1F), 2-AA labelled (FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide, 2-AA labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    FA2[3]G1 & FA2[6]G1 glycan (G1F), 2-AA labelled
  • HY-158478
    FA2[3]G1 & FA2[6]G1 glycan (G1F), 2-AB labelled

    FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide, 2-AB labelled

    		 Biochemical Assay Reagents Others
    FA2[3]G1 & FA2[6]G1 glycan (G1F), 2-AB labelled (FA2[3]G1 & FA2[6]G1 N-linked oligosaccharide, 2-AB labelled) is a N-polysaccharide protein and a multifunctional fluorescent linker. The resulting conjugates exhibit high sensitivity and specificity by mimicking the antennal elements of N-glycans .
    FA2[3]G1 & FA2[6]G1 glycan (G1F), 2-AB labelled
  • HY-169047
    PAMAM dendrimer G1.5 carboxylate sodium

    PAMAM G1.5 carboxylate sodium

    		 SARS-CoV Infection
    PAMAM dendrimer G1.5 carboxylate (PAMAM G1.5 carboxylate) sodium is a polyanionic dendrimers comprising the terminal groups sodium carboxylate. PAMAM dendrimer G1.5 carboxylate shows antiviral activity with the MERS‐CoV plaque inhibition assay, with the inhibition rate of 40.5% .
    PAMAM dendrimer G1.5 carboxylate sodium
  • HY-160580
    G1-OC2-K3-E10

    		Liposome Others
    G1-OC2-K3-E10 is an ionizable lipid, and can be used for delivery of mRNA in lipid nanoparticles (LNPs) .
    G1-OC2-K3-E10
  • HY-158861
    C3-K2-E14

    G1-nPr-C14E

    		 Liposome Others
    C3-K2-E14 is a multi-ionizable amino-lipid featuring a central tertiary amine with two identical branches and an n-propyl group. Each branch features a propanamide linking to a branched amine, each with two C14 arms and a hydroxyl. Ionizable lipids such as this may be applied in the development of lipid nanoparticles for drug discovery.
    C3-K2-E14
  • HY-N17987
    Hemsloside G1

    		Others Others
    Hemsloside G1 is a saponin that found in the rhizome of Hemsleya graciliflora .
    Hemsloside G1
  • HY-129848
    Cucumarioside G1

    		Others Others
    Cucumarioside G1 is a triterpene glycoside and can be isolated from Cucumaria fraudatrix .
    Cucumarioside G1

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: