24 Results for "

Glycolic acid

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Glycolic acid" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W015967
CAS No.: 79-14-1
Synonyms: Hydroxyethanoic acid
Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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32 Publications Verification
Cat. No.: HY-B2247
CAS No.: 34346-01-5
Synonyms: poly(lactic-co-Glycolic acid) (50:50)
PLGA (50:50) (poly(lactic-co-glycolic acid) (50:50)) is a copolymer of poly lactic acid (PLA) and poly glycolic acid (PGA) which can be used to fabricate devices for drug delivery and tissue engineering applications.
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7
7 Cited Publications
Cat. No.: HY-B2247A
CAS No.: 34346-01-5
Synonyms: poly(lactic-co-Glycolic acid) (75:25)
Research Areas:  

Others

PLGA (75:25) is a low toxicity, biocompatible and biodegradable controlled drug delivery carrier, can achieve slow release in the organism. PLGA (75:25) is a copolymer of 75% poly lactic acid (PLA) and 25% poly glycolic acid (PGA). PLGA (75:25) has been extensively studied as delivery vehicles for agents, proteins and various other macromolecules such as DNA, RNA and peptides .
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1
1 Cited Publications
Cat. No.: HY-158089
Purity:  ≥95.0%
Research Areas:  

Others

PLGA-COOH (MW 80000) (LA/GA 50:50) is a copolymer composed of lactic acid (LA)-glycolic acid (GA) at a molar ratio of 50:50 and a terminal carboxyl group. PLGA-COOH (MW 80000) (LA/GA 50:50) is used in compound delivery systems due to its biocompatibility and biodegradability .
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1
1 Cited Publications
Cat. No.: HY-148775B
Purity:  ≥95.0%
PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) is a biodegradable amphipathic polymeric nanocarrier of poly (lactic-co-glycolic acid)-block-poly (ethylene glycol) (PLGA-PEG-Mal) that allows covalent modification of functional molecules. PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) modified with Angiopep-2 can cross the blood-brain barrier and exhibits targeting selectivity for glioblastoma cells. PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) can capture tumor-derived protein antigens, and exerts immunomodulatory effects when conjugated with anti-OX40 antibody; when used in combination with A2-CL/Dbait nanoparticles and radiotherapy, it prolongs survival time and reduces tumor volume in glioblastoma mouse models. PLGA-PEG-MAL (20KDA-5.0KDA, LA:GA RATIO 40:60) can be used for studies related to bacterial wound infections and glioblastoma .
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Cat. No.: HY-W723152
CAS No.: 26780-50-7
Target:  

Drug Intermediate

Research Areas:  

Inflammation/Immunology

Poly(D,L-lactide-co-glycolide) is a biodegradable polymer copolymer. Poly(D,L-lactide-co-glycolide) undergoes degradation through ester bond hydrolysis into lactic acid and glycolic acid. These two products can be naturally eliminated through metabolism in the body (such as the tricarboxylic acid cycle), without the risk of long-term accumulation. Poly(D,L-lactide-co-glycolide) can be used in medical sutures, implants, and drug delivery systems .
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Cat. No.: HY-B0482
CAS No.: 53164-05-9
Synonyms: TVX 1322
Target:  

COX

Research Areas:  

Inflammation/Immunology

Acemetacin (TVX 1322) is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.
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Cat. No.: HY-W015967S
CAS No.: 75502-10-2
Glycolic acid-d2 is the deuterium labeled Glycolic acid. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-W039233
CAS No.: 2359705-88-5
Target:  

Ligands for E3 Ligase

Research Areas:  

Cancer

Lenalidomide-F is a CRBN ligand. Lenalidomide-F can be conjugated with the FLT3 ligand Gilteritinib (HY-12432) via the linker Glycolic acid (HY-W015967) to synthesize the FLT3 PROTAC degrader LWY713 (HY-157213). Lenalidomide-F is applicable to the research of acute myeloid leukemia .
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Cat. No.: HY-148775A
CAS No.: 743423-15-6
MPEG-PLGA (21500-26500) is a biodegradable amphipathic polymeric nanocarrier of poly (lactic-co-glycolic acid)-block-poly (ethylene glycol) (PLGA-PEG-Mal) that allows covalent modification of functional molecules. MPEG-PLGA (21500-26500) modified with Angiopep-2 can cross the blood-brain barrier and exhibits targeting selectivity for glioblastoma cells. MPEG-PLGA (21500-26500) can capture tumor-derived protein antigens, and exerts immunomodulatory effects when conjugated with anti-OX40 antibody; when used in combination with A2-CL/Dbait nanoparticles and radiotherapy, it prolongs survival time and reduces tumor volume in glioblastoma mouse models. MPEG-PLGA (21500-26500) can be used for studies related to bacterial wound infections and glioblastoma .
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Cat. No.: HY-156829A
Research Areas:  

Cancer

PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 15:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 15:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
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Cat. No.: HY-156829
Research Areas:  

Cancer

PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) is a matrix materia, with lactic acid (LA):glycolic acid (GA) = 1:1, that acts as anti-cancer drug delivery. PLGA-PEG-PLGA (1500-1500-1500) (LA/GA 1:1) can improve a drug's bioavailability, efficacy, water solubility, drug encapsulation efficiency, sustained drug release, and to minimize undesirable toxicity .
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Cat. No.: HY-148776
PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) is a degradable amphiphilic polymer nanocarrier of poly (lactic acid-co-glycolic acid)-block-poly (ethylene glycol) (PLGA-PEG-Mal) that allows covalent modification of functional molecules. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) serves as a core polymer for nanoparticle synthesis, and also acts as a nanoparticle component for site-specific antibody conjugation to construct artificial antigen-presenting cells. PLGA-PEG-MAL (20kDA-5.0kDA, LA:GA ratio 50:50) is applicable for drug delivery-related research .
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Cat. No.: HY-22166
CAS No.: 77529-42-1
Target:  

Others

Research Areas:  

Metabolic Disease

Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor, extracted from patent EP0021228A1, in Table IV.
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Cat. No.: HY-W778203
CAS No.: 111389-68-5
Synonyms: Hydroxyethanoic acid-13C2
Glycolic acid- 13C2 is the 13C-labeled Glycolic acid (HY-W015967). Glycolic acid- 13C2 is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-148775
Purity:  ≥95.0%
PLGA-PEG-MAL (60kDa-3.4kDa, LA:GA ratio 75:25) is a biodegradable amphipathic polymeric nanocarrier of poly (lactic-co-glycolic acid)-block-poly (ethylene glycol) (PLGA-PEG-Mal) that allows covalent modification of functional molecules. PLGA-PEG-MAL (60kDa-3.4kDa, LA:GA ratio 75:25) modified with Angiopep-2 can cross the blood-brain barrier and exhibits targeting selectivity for glioblastoma cells. PLGA-PEG-MAL (60kDa-3.4kDa, LA:GA ratio 75:25) can capture tumor-derived protein antigens, and exerts immunomodulatory effects when conjugated with anti-OX40 antibody; when used in combination with A2-CL/Dbait nanoparticles and radiotherapy, it prolongs survival time and reduces tumor volume in glioblastoma mouse models. PLGA-PEG-MAL (60kDa-3.4kDa, LA:GA ratio 75:25) can be used for studies related to bacterial wound infections and glioblastoma .
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Cat. No.: HY-158255A
CAS No.: 743423-15-6
Purity:  ≥95.0%
Research Areas:  

Others

mPEG-PLGA (22500-26500) is a biodegradable polymer composed of methyl polyethylene glycol (mPEG) and poly(lactic-co-glycolic acid) (PLGA). mPEG-PLGA (22500-26500) can be used in drug delivery systems .
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Cat. No.: HY-W015967R
CAS No.: 79-14-1
Synonyms: Hydroxyethanoic acid (Standard)
Glycolic acid (Standard) is the analytical standard of Glycolic acid. This product is intended for research and analytical applications. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
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Cat. No.: HY-D0153
CAS No.: 80724-19-2
Tetramethylrhodamine-5-isothiocyanate is a potent fluorescent dye. Tetramethylrhodamine-5-isothiocyanate can be used for label PG-M3 antibody for rapid diagnosis of acute promyelocytic leukemia (APL). Tetramethylrhodamine-5-isothiocyanate can be used as probe to quantify in vivo the biodistribution of PLGA (poly(lactic-co-glycolic) acid) and PLGA/chitosan nanoparticles .
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Cat. No.: HY-169373
CAS No.: 2229976-15-0
Research Areas:  

Others

Lenalidomide-Glycolic acid is a E3 Ligase Ligand-Linker Conjugate for PROTAC-class FLT3 degrader LWY713 (HY-157213) .
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