Lenalidomide-F
Based on 1 Customer Validation
Lenalidomide-F is a CRBN ligand. Lenalidomide-F can be conjugated with the FLT3 ligand Gilteritinib (HY-12432) via the linker Glycolic acid (HY-W015967) to synthesize the FLT3 PROTAC degrader LWY713 (HY-157213). Lenalidomide-F is applicable to the research of acute myeloid leukemia.
For research use only. We do not sell to patients.
- Purity: 99.44%
- CAS No.: 2359705-88-5
- Formula: C13H11FN2O3
- Molecular Weight:262.24
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
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Cereblon |
Chemical Information
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CAS No. 2359705-88-5
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Appearance Solid
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Molecular Weight 262.24
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Formula C13H11FN2O3
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Color Light blue to gray
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SMILES
O=C(C(N(CC1=C2C=CC=C1F)C2=O)CC3)NC3=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 5 mg/mL (19.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8133 mL | 19.0665 mL | 38.1330 mL | 95.3325 mL |
| 5 mM | 0.7627 mL | 3.8133 mL | 7.6266 mL | 19.0665 mL | |
| 10 mM | 0.3813 mL | 1.9067 mL | 3.8133 mL | 9.5333 mL | |
| 15 mM | 0.2542 mL | 1.2711 mL | 2.5422 mL | 6.3555 mL |