17 Results for "

Gynostemma pentaphyllum

" in MedChemExpress (MCE) Product Catalog:
Products (17)

17 Results for "Gynostemma pentaphyllum" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-N8211
CAS No.: 94987-09-4
Gypenoside L is a saponin that can be found in Gynostemma pentaphyllum. Gypenoside L increases the SA-β-galactosidase activity, promotes the production of senescence-associated secretory cytokines. Gypenoside L also can activate p38 and ERK MAPK pathways and NF-κB pathway to induce senescence. Gypenoside L exhibits anti-tumor and anti-inflammatory activities .
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2 Cited Publications
Cat. No.: HY-N1990
CAS No.: 94987-08-3
Gypenoside XLIX is a multifunctional bioactive compound that can be isolated from Gynostemma pentaphyllum, with a Ka value of 1.58 μM for its binding to SIRT1. Gypenoside XLIX acts as a PPAR-α agonist. It inhibits the activation of TLR4-mediated NF-κB signaling pathway by activating the Sirt1/Nrf2 signaling pathway, reduces ROS accumulation, and alleviates hepatic inflammatory injury in mice with sepsis-induced liver disease. Gypenoside XLIX targets SIRT1 to block YAP-NLRP3 activation and improve sepsis-induced cardiomyopathy. Gypenoside XLIX inhibits apoptosis (Apoptosis), pyroptosis (Pyroptosis), autophagy (Autophagy), lipid peroxidation, pro-inflammatory cytokines and anti-inflammatory cytokines. Gypenoside XLIX alleviates sepsis-induced splenic injury by inhibiting inflammation and oxidative stress, and mitigates sepsis-associated encephalopathy by targeting PPAR-α. Gypenoside XLIX prevents acute kidney injury by inhibiting IGFBP7/IGF1R-mediated programmed cell death and inflammation. Gypenoside XLIX inhibits the expression and activity of vascular cell adhesion molecule-1 in cytokine-induced human endothelial cells. Gypenoside XLIX is applicable to research related to acute liver injury, lung injury, cardiomyopathy, acute splenic injury, sepsis-associated encephalopathy, acute kidney injury, atherosclerosis and chronic inflammation .
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1
1 Cited Publications
Cat. No.: HY-N2440
CAS No.: 157752-01-7
Gypenoside A is an orally active triterpenoid compound that can be isolated from Gynostemma pentaphyllum. Gypenoside A has anti-inflammatory and antioxidant activities. Gypenoside A also has a certain protective effect on cardiomyocytes and can inhibit apoptosis. Gypenoside A can be used in the research of cardiovascular diseases and inflammation-related diseases .
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1 Cited Publications
Cat. No.: HY-16942
CAS No.: 1202868-75-4
Damulin B is a dammarane-type saponin found in Gynostemma pentaphyllum. Damulin B can inhibit cancer cell apoptosis, decrease mitochondrial membrane potential, inhibit ROS production and cause G0/G1 phase arrest. Damulin B can prevent Cisplatin (HY-17394)-induced acute kidney injury and induce hair growth. Damulin B shows anti-inflammation anti-diabetic and anti-obesity effect. Damulin B can be used for the researches of cancer, inflammation, metabolic disease, such as lung cancer, osteoarthritis and diabetes .
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1 Cited Publications
Cat. No.: HY-N6881
CAS No.: 80325-22-0
Gypenoside XIII is belonging to the gypenosides. Gypenosides, extracted from Gynostemma pentaphyllum, have various pharmacological properties and protect against cardiovascular diseases, especially atherosclerosis .
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1 Cited Publications
Cat. No.: HY-N7678
CAS No.: 110261-98-8
Gypenoside LXXV, isolated from Gynostemma pentaphyllum, is one of the deglycosylated shapes of ginsenoside Rb1. Gypenoside LXXV significantly reduces cancer cell viability and displays an anti-cancer effect .
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Cat. No.: HY-N21253
Gynostemma pentaphyllum polysaccharide is a polysaccharide derived from Gynostemma pentaphyllum.
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Cat. No.: HY-N12327
CAS No.: 158642-42-3
Ombuin-3-O-glucoside is a flavonoid glycoside derived from Gynostemma pentaphyllum. Ombuin-3-O-glucoside has antioxidant activity .
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Cat. No.: HY-N3983
CAS No.: 1207861-69-5
Gynosaponin I (compound 1) is a natural product that can be found in Gynostemma pentaphyllum .
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Cat. No.: HY-N17991
CAS No.: 2793436-99-2
Gypenoside XCI is a glycoside found in Gynostemma pentaphyllum .
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Cat. No.: HY-N17994
CAS No.: 862286-50-8
GypenosideZ-2 is a dammarane-type triterpene saponin found in the aerial parts of Gynostemma pentaphyllum (Thunb.) Makino .
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Cat. No.: HY-N9906
CAS No.: 53585-54-9
Kaempferol-7-O-β-D-galactopyranoside is a flavonoid glycoside found in the aerial parts of Gynostemma pentaphyllum with no significant antiproliferative activity against cancer cells .
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Cat. No.: HY-N18048
CAS No.: 134355-16-1
Gypenoside CII is a dammarane-type triterpene saponin that can be isolated from Gynostemma pentaphyllum. Gypenoside CII exerts no significant activating effect on recombinant human Sirt1, while its congeners are potent Sirt1 agonists .
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Cat. No.: HY-N17992
CAS No.: 1443433-27-9
Gypenoside UL5 (Compound UL5) is a dammarane-type triterpene saponin found in Gynostemma pentaphyllum. Gypenoside UL5 shows liver injury-inhibiting, anti-inflammatory and antioxidant properties. Gypenoside UL5 can be used for the research of hepatitis, fatty liver, and liver fibrosis .
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Cat. No.: HY-N17993
CAS No.: 862286-49-5
GypenosideZ-1 is a triterpenoid saponin found in Gynostemma pentaphyllum .
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Cat. No.: HY-N18005
CAS No.: 109150-50-7
Gypenoside LXIX (Compound 4) is a glycoside found in the aerial parts of Gynostemma pentaphyllum .
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Cat. No.: HY-N18006
CAS No.: 250217-53-9
Otophylloside C is a C21 steroidal glycoside compound found in the root of Gynostemma pentaphyllum .
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