4 Results for "

HEK-293T cell line

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "HEK-293T cell line" in MCE Product Catalog:

16
16 Cited Publications
Cat. No.: HY-15888
CAS No.: 315704-66-6
Purity:  99.76%
Target:  

BMI1 Autophagy

Research Areas:  

Cancer

PTC-209 is a specific BMI-1 inhibitor with an IC50 of 0.5 μM in HEK293T cell line. PTC-209 irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 shows potent anti-myeloma activity and impairs the tumor microenvironment .
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16
16 Cited Publications
Cat. No.: HY-15888A
CAS No.: 1217022-63-3
Purity:  99.44%
Target:  

BMI1 Autophagy

Research Areas:  

Cancer

PTC-209 hydrobromide is a specific BMI-1 inhibitor with an IC50 of 0.5 μM in HEK293T cell line. PTC-209 hydrobromide irreversibly impairs colorectal cancer-initiating cells (CICs). PTC-209 hydrobromide shows potent anti-myeloma activity and impairs the tumor microenvironment .
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Cat. No.: HY-179475
CAS No.: 1262781-19-0
Target:  

CaSR

Research Areas:  

Endocrinology

KP-2067 is a form of the CaSR agonist peptide. KP-2067 can result in dose-dependent activation of CaSR in HEK293T overexpressing hCaSR cell line, with an EC50 of 18.4 μM. KP-2067 significantly reduces plasma parathyroid hormone in rat model .
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Cat. No.: HY-186073
CAS No.: 300399-36-4
Target:  

HDAC

Research Areas:  

Neurological Disease

HDAC1 activator-1 is a specific HDAC1 activator with orally activity, exerting no significant effects on other HDAC family members. HDAC1 activator-1 exhibits neuroprotective activity, ameliorates cognitive and motor function deficits by reducing neuronal loss and gliosis. HDAC1 activator-1 specifically activates HDAC1 in SH-SY5Y cells and exerts regulatory effects on aberrant cell cycle and DNA damage. HDAC1 activator-1 can be used for the research of TDP-43 proteinopat1-related neurodegenerative diseases including Amyotrophic Lateral Sclerosis (ALS) and cerebral ischemia-related neurological injury .
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