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HIV envelope protein

" in MedChemExpress (MCE) Product Catalog:

By Targets:	HIV (3) Bacterial (1) CD3 (1) Dengue Virus (1)
By Research Areas:	Infection (3)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Targets Recommended: HIV Integrase HIV HIV Protease

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P991069

VRC-01	HIV	Infection
VRC-01 is a broadly neutralizing IgG1 monoclonal antibody that targets *HIV-1* envelope glycoprotein gp120 Protein. VRC-01 blocks HIV-1 viral entry by mimicking CD4 receptor interaction with HIV-1 gp120 and neutralizes broad HIV-1 clades. VRC-01 can be used for the research of HIV-1 infection .

HY-P991479

Amtabafusp alfa GS-8588	HIV CD3	Infection
Amtabafusp alfa (GS-8588) is an envelope-targeting bispecific T-cell engager for *HIV* treatment. Amtabafusp alfa redirects effector T cells by binding to CD3 via a humanized anti-CD3 Fab domain and to HIV envelope proteins via an engineered CD4 domain 1 variant. Amtabafusp alfa exhibits potent, broad-spectrum activity against a variety of HIV isolates and specifically kills HIV-infected cells. Amtabafusp alfa can be used for research on HIV infection .

HY-182588

Circulin B	Bacterial HIV Dengue Virus	Infection
Circulin B is a macrocyclic plant cyclopeptide. Circulin B functions as a plant defense peptide and exhibits antibacterial and anti-HIV activities. Circulin B has high binding affinity for the envelope protein of dengue virus, showing potential anti-dengue virus activity. Circulin B can be used in studies related to dengue virus infection, human immunodeficiency virus infection and microbial infection .

Cat. No.	Product Name	Target	Research Area	Image

HY-P991069

VRC-01	HIV	Infection
VRC-01 is a broadly neutralizing IgG1 monoclonal antibody that targets *HIV-1* envelope glycoprotein gp120 Protein. VRC-01 blocks HIV-1 viral entry by mimicking CD4 receptor interaction with HIV-1 gp120 and neutralizes broad HIV-1 clades. VRC-01 can be used for the research of HIV-1 infection .

HY-P991479

Amtabafusp alfa GS-8588	HIV CD3	Infection
Amtabafusp alfa (GS-8588) is an envelope-targeting bispecific T-cell engager for *HIV* treatment. Amtabafusp alfa redirects effector T cells by binding to CD3 via a humanized anti-CD3 Fab domain and to HIV envelope proteins via an engineered CD4 domain 1 variant. Amtabafusp alfa exhibits potent, broad-spectrum activity against a variety of HIV isolates and specifically kills HIV-infected cells. Amtabafusp alfa can be used for research on HIV infection .

Species:	Virus (9)
Tag:	His (9) Avi (1)
Source:	HEK293 (9)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P74885

	envelope glycoprotein gp160 Protein, HIV-1 (AAT67478, HEK293, His) HIV-1 (group M, subtype A, isolate 92RW020) envelope glycoprotein gp160 protein (gp120 subunit) (His)	Virus	HEK293
	gp160 is an envelope glycoprotein that oligomerizes into major trimers in the host endoplasmic reticulum.gp160 is transported in the host Golgi apparatus to complete the glycosylation process.The precursors are proteolytic cleaved in the trans-Golgi apparatus to produce gp120 and gp41.envelope glycoprotein gp160 Protein, HIV-1 (AAT67478, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp160 protein, expressed by HEK293 , with C-His labeled tag.

HY-P705392

	gp140 Protein, HIV-1 (Biotinylated, HEK293, His-Avi) Human immunodeficiency virus 1 (HIV-1); envelope glycoprotein gp140/gp140 (HIV)	Virus	HEK293

HY-P70907

	Envelope glycoprotein gp120 Protein, HIV (Q9DKG6, HEK293, His) 1 Publications Verification envelope glycoprotein gp120; Glycoprotein 120; Surface protein gp120	Virus	HEK293
	The envelope glycoprotein gp120 protein facilitates viral capture and dissemination by dendritic cells and endothelial cells by attaching the virus to host lymphocytes through binding to the CD4 receptor. HIV exploits the migratory properties of dendritic cells to access CD4+ T cells, leading to infection. Envelope glycoprotein gp120 Protein, HIV (Q9DKG6, HEK293, His) is the recombinant Virus-derived Envelope glycoprotein gp120 protein, expressed by HEK293 , with C-8*His labeled tag.

HY-P74118

	envelope glycoprotein gp120 Protein, HIV-1 (ACY40659, HEK293, His) envelope glycoprotein gp160; Env polyprotein; gp120; gp41; env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (ACY40659, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74119

	envelope glycoprotein gp120 Protein, HIV-1 (AFM77980, HEK293, His) envelope glycoprotein gp160; Env polyprotein; gp120; gp41; env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (AFM77980, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74120

	envelope glycoprotein gp120 Protein, HIV-1 (AAC57427, HEK293 , His) envelope glycoprotein gp160; Env polyprotein; gp120; gp41; env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (AAC57427, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74121

	envelope glycoprotein gp120 Protein, HIV-1 (AAA44191, HEK293 , His) envelope glycoprotein gp160; Env polyprotein; gp120; gp41; env	Virus	HEK293
	envelope glycoprotein gp120 Protein is a glycoprotein exposed on the surface of the HIV envelope.Gp120 is essential for viral infection as it facilitates HIV entry into the host cell.gp120 may also be facilitating viral persistence and continuing HIV infection by influencing the T cell immune response to the virus.envelope glycoprotein gp120 Protein, HIV-1 (AAA44191, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-10*His labeled tag.

HY-P76383

	envelope glycoprotein gp160 Protein, HIV-1 (ADD25380, HEK293, His) HIV-1 gp160 protein (gp120 subunit) (group N, strain 06CM-U14296)	Virus	HEK293
	Envelope glycoprotein gp160 Protein (HIV-1 gp160 Protein) is the sole antigenic protein on the surface of the HIV-1 virion and mediates HIV-1 entry into target cells. The endoproteolytic processing of HIV-1 gp160 membrane glycoprotein precursor into gp120 and gp41 is necessary for formation of infectious HIV particles. HIV-1 gp160 induces endothelial cell apoptosis, which is mediated by CXCR4 chemokine receptor. envelope glycoprotein gp160 Protein, HIV-1 (ADD25380, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp160 protein, expressed by HEK293 , with C-His labeled tag.

HY-P76390

	envelope glycoprotein gp120 Protein, HIV-1 (AAC31819, HEK293, His) Human immunodeficiency virus 1 (HIV-1) (group M, subtype B, Isolate MN) gp120 protein (His)	Virus	HEK293
	The envelope glycoprotein gp120 protein facilitates viral capture and dissemination by dendritic cells and endothelial cells by attaching the virus to host lymphocytes through binding to the CD4 receptor.HIV exploits the migratory properties of dendritic cells to access CD4+ T cells, leading to infection.envelope glycoprotein gp120 Protein, HIV-1 (AAC31819, HEK293, His) is the recombinant Virus-derived envelope glycoprotein gp120 protein, expressed by HEK293 , with C-His labeled tag.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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