20905-50-4
Chemical Structure
Circulin B
- CAS No.: 20905-50-4
- Formula:C52H98N16O13
- Molecular Weight:1155.43
InChIKey: DRHFCEIZVVAMEH-GZQYODANSA-N
SMILES: CC(C)CCCCC(N[C@@H](CCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCN)C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1)=O)([H])[C@H](O)C)=O)CCN)=O)CCN)=O)([H])[C@@H](C)CC)=O)CC(C)C)=O)CCN)=O)=O)=O)=O)=O
Biological Activity: Circulin B is a macrocyclic plant cyclopeptide. Circulin B functions as a plant defense peptide and exhibits antibacterial and anti-HIV activities. Circulin B has high binding affinity for the envelope protein of dengue virus, showing potential anti-dengue virus activity. Circulin B can be used in studies related to dengue virus infection, human immunodeficiency virus infection and microbial infection[1][2].
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Circulin B | Circulin B is a macrocyclic plant cyclopeptide. Circulin B functions as a plant defense peptide and exhibits antibacterial and anti-HIV activities. Circulin B has high binding affinity for the envelope protein of dengue virus, showing potential anti-dengue virus activity. Circulin B can be used in studies related to dengue virus infection, human immunodeficiency virus infection and microbial infection. | |||||||||||||||||||||
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References
- [1]. Reena G, et al. In silico screening of plant peptides against the envelope protein of dengue virus. Trop Biomed. 2023;40(2):124-128. [Content Brief]
- [2]. Balaraman S, et al. The structural and functional reliability of Circulins of Chassalia parvifolia for peptide therapeutic scaffolding. J Cell Biochem. 2018;119(5):3999-4008. [Content Brief]
