Circulin B
Circulin B is a macrocyclic plant cyclopeptide. Circulin B functions as a plant defense peptide and exhibits antibacterial and anti-HIV activities. Circulin B has high binding affinity for the envelope protein of dengue virus, showing potential anti-dengue virus activity. Circulin B can be used in studies related to dengue virus infection, human immunodeficiency virus infection and microbial infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 20905-50-4
- Formel: C52H98N16O13
- Molecular Weight:1155.43
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Vero | CC50 |
199 μg/mL
Compound: Polymyxin E2-Ile
|
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay
|
[PMID: 29412662] |
In Vitro
Circulin B exhibits non-allergenic and non-toxic properties in in silico profiling[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 20905-50-4
-
Molecular Weight 1155.43
-
Formel C52H98N16O13
-
SMILES
CC(C)CCCCC(N[C@@H](CCN)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCN)C(N[C@@H]1C(N[C@H](C(N[C@@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C(NCC1)=O)([H])[C@H](O)C)=O)CCN)=O)CCN)=O)([H])[C@@H](C)CC)=O)CC(C)C)=O)CCN)=O)=O)=O)=O)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Reena G, et al. In silico screening of plant peptides against the envelope protein of dengue virus. Trop Biomed. 2023;40(2):124-128. [Content Brief]
[2]. Balaraman S, et al. The structural and functional reliability of Circulins of Chassalia parvifolia for peptide therapeutic scaffolding. J Cell Biochem. 2018;119(5):3999-4008. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Circulin B Related Classifications
HY-182588 Related Classifications
Powered by Bioz
Keywords
- Circulin B
- 20905-50-4
- Bacterial
- HIV
- Dengue Virus
- microbial infections
- dengue virus envelope protein
- fusion inhibition activity
- dengue virus infection
- human immunodeficiency virus infection
- human immunodeficiency virus
- *Chassalia parvifolia*
- intramolecular interactions
- plant defensive peptide
- antimicrobial activity
- Inhibitor
- inhibitor
- inhibit