1 Result for "

HPGDS inhibitor-3

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "HPGDS inhibitor-3" in MCE Product Catalog:

Cat. No.: HY-146662
CAS No.: 2255311-93-2
Target:  

PGE synthase

Research Areas:  

Inflammation/Immunology

HPGDS inhibitor 3 is an orally active and highly potent peripherally restricted hematopoietic prostaglandin D synthase (H-PGDS) inhibitor with IC50 value of 9.4 nM and EC50 of 42 nM, respectively. HPGDS inhibitor 3 exhibits good selectivity, good pharmacokinetic parameters in mouse, rat, and dog, and no CNS toxicity. HPGDS inhibitor 3 has anti-inflammatory activity .
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