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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Hpcal1
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Hpcal1" in MCE Product Catalog:
Cat. No.: HY-177554
CAS No.: 2724919-69-9
Target:
Research Areas:
KB05yne is a site-selective, alkyne-functionalized electrophilic "probe" fragment probe designed for covalent ligand discovery, with preferential reactivity toward specific cysteine residues in proteins. KB05yne strongly labels wild-type target proteins (e.g., CDKN2AIP, HPCAL1) but does not label their cysteine-to-alanine mutants, confirming site-specific cysteine reactivity. KB05yne can be used for the discovery and optimization of site-specific covalent ligands, and is applicable to proteins with diverse structures and functions, especially in studies targeting cysteine residues in cancer-related or difficult-to-purify proteins [1].
Cat. No.: HY-RS06334
Target:
Research Areas:
HPCAL1 Human Pre-designed siRNA Set A contains three designed siRNAs for HPCAL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19260
Target:
Research Areas:
Hpcal1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Hpcal1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS25749
Target:
Research Areas:
Hpcal1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Hpcal1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70346
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Hpcal1; HLP2; Hippocalcin Like 1; Calcium-Binding Protein BDR-1; VILIP-3; Hippocalcin-Like Protein 1; BDR1; Visinin-Like Protein 3; rHuHippocalcin-like protein 1/Hpcal1, His; HLP2
Species:
Human
Source:
E. coli
Cat. No.: HY-185414
CAS No.: 2724919-70-2
Target:
Research Areas:
KB05-Biotin is streptavidin-conjugated KB05 (HY-149461) that retains the site-specific cysteine covalent reactivity of KB05, enabling specific detection of target proteins via the biotin-streptavidin system. KB05-Biotin serves as a site-specific probe in ELISA-ABPP assays for screening electrophilic small molecules that bind to scout fragment-sensitive cysteines on target proteins in cell lysates, without the need for protein purification [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
