26 Results for "

IGF-I receptor

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "IGF-I receptor" in MCE Product Catalog:

6
6 Publications Verification
Cat. No.: HY-16381
CAS No.: 396091-73-9
Synonyms: SOM230
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology Cancer

Pasireotide (SOM230), a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide also exhibits antisecretory, antiproliferative, and proapoptotic activity .
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2
2 Cited Publications
Cat. No.: HY-16381A
CAS No.: 396091-76-2
Synonyms: SOM230 acetate
Target:  

Somatostatin Receptor

Research Areas:  

Endocrinology Cancer

Pasireotide (SOM230) acetate, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide acetate can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide acetate also exhibits antisecretory, antiproliferative, and proapoptotic activity .
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2
2 Cited Publications
Cat. No.: HY-P78723
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; IGFR; IGF1R Protein
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-108905
CAS No.: 68562-41-4
Synonyms: Human IGF-I; FK 780
Target:  

IGF-1R

Research Areas:  

Metabolic Disease

Mecasermin (Human IGF-I; FK 780) is a recombinant human insulin-like growth factor I (IGF-I). Mecasermin has the potential for the study of the growth failure of growth hormone (GH) insensitivity caused by GH receptor defects or GH-inhibiting antibodies .
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Cat. No.: HY-P3226
CAS No.: 147819-32-7
JB-1, an IGF-I analog, is a selective IGF-I receptor inhibitor that does not interact with IGF-II. JB-1 competes with IGF-I for binding to IGF-1R and blocks receptor autophosphorylation. JB-1 increases the level of sVEGFR-1. JB-1 normalizes retinal abnormalities, including reducing retinal neovascularization. JB-1 is applicable to studies related to oxygen-induced retinopathy .
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Cat. No.: HY-175053
Synonyms: SOM230 (aspartate) TFA
Research Areas:  

Metabolic Disease

Pasireotide (aspartate) TFA, a long-acting cyclohexapeptide somatostatin analogue, can improve agonist activity at somatostatin receptors (subtypes sst1/2/3/4/5, pKi=8.2/9.0/9.1/<7.0/9.9, respectively). Pasireotide (aspartate) TFA can suppress GH, IGF-I and ACTH secretion, indicating potential efficacy in acromegaly and Cushing's disease. Pasireotide (aspartate) TFA also exhibits antisecretory, antiproliferative, and proapoptotic activity .
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Cat. No.: HY-P86629
Synonyms: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human

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Cat. No.: HY-174649
Target:  

mRNA

Research Areas:  

Metabolic Disease

Human IGFBP4 mRNA encodes the human insulin like growth factor binding protein 4 (IGFBP4) protein, a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 can bind both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors.
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Cat. No.: HY-174650
Target:  

mRNA

Research Areas:  

Metabolic Disease

Human IGFBP3 mRNA encodes the human insulin like growth factor binding protein 3 (IGFBP3) protein, a member of the insulin-like growth factor binding protein (IGFBP) family. IGFBP3 can form a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.
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Cat. No.: HY-P85213
Synonyms: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Host:  

Mouse

Application:  

IHC-P, ELISA

Reactivity:  

Human

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Cat. No.: HY-P85214
Synonyms: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Host:  

Mouse

Application:  

IHC-P, ELISA

Reactivity:  

Human

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Cat. No.: HY-P72256
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P74442
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P73137
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P78458
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78142
Purity:  ≥ 90%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P86076
Synonyms: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221; INSR; Insulin receptor; IR; CD antigen CD220

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P704676
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72606
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78724
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGF1R; IGF-I receptor; Insulin Like Growth Factor 1 receptor; MGC18216; Insulin-Like Growth Factor 1 receptor; Insulin-Like Growth Factor I receptor; JTK13; receptor Protein-Tyrosine Kinase; CD221; Tyrosine-Protein Kinase receptor; IGFIR; CD221 Antigen; I
Species:  
Rat
Source:  
HEK293
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