2 Results for "

IL-6/IL-6Rα

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "IL-6/IL-6Rα" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P990211

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse IL-6R Antibody (15A7) is a rat-derived anti-mouse IL-6R IgG2b κ type antibody inhibitor. Anti-Mouse IL-6R Antibody (15A7) blocks IL-6 binding to IL-6Rα and inhibits both IL-6 classic and trans-signaling. Anti-Mouse IL-6R Antibody (15A7) can be used for the researches of cancer and inflammation, such as triple-negative breast cancer .
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Cat. No.: HY-P9916
CAS No.: 1189541-98-7
Synonyms: Anti-Human IL6Rα, Human Antibody
Sarilumab is a monoclonal antibody targeting IL6 that binds to IL6R and blocks the binding of IL6, thereby inhibiting the activation of the downstream STAT3 phosphorylation signaling pathway. In tumor cells with active IL6/STAT3 signaling pathways, Sarilumab induces Apoptosis and inhibits cell growth. Sarilumab is applicable to research related to prostate cancer, lung cancer and rheumatoid arthritis .
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