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Sarilumab

(Synonyms: Anti-Human IL6Rα, Human Antibody)
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Based on 1 Customer Validation

Sarilumab is a monoclonal antibody targeting IL6 that binds to IL6R and blocks the binding of IL6, thereby inhibiting the activation of the downstream STAT3 phosphorylation signaling pathway. In tumor cells with active IL6/STAT3 signaling pathways, Sarilumab induces Apoptosis and inhibits cell growth. Sarilumab is applicable to research related to prostate cancer, lung cancer and rheumatoid arthritis.

For research use only. We do not sell to patients.

  • Purity: 99.36%
  • CAS No.: 1189541-98-7
  • Molecular Weight:144.12 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Sarilumab
  • Experimental Validation Results for Sarilumab
  • Sarilumab Chemical Structure
    Sarilumab Chemical Structure
CAS No.: 1189541-98-7
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Use of MCE Products

All Interleukin Related Isoforms

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All STAT Isoforms

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100 mg

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized IL-6R alpha Protein, Human can bind Sarilumab. The EC50 for this effect is 34.98 ng/mL.

  • Sarilumab Chemical Structure
    1/16
  • Sarilumab
  • Immobilized IL-6R alpha Protein, Human can bind Sarilumab. The EC50 for this effect is 34.98 ng/mL.