2. Immunology/Inflammation
  3. Interleukin Related
  4. Sarilumab

Sarilumab  (Synonyms: Anti-Human IL6Rα, Human Antibody)

Cat. No.: HY-P9916 Purity: 98.36%
COA

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Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis.

For research use only. We do not sell to patients.

Sarilumab Chemical Structure

Sarilumab Chemical Structure

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1 mg USD 235 In-stock
5 mg USD 680 In-stock
10 mg USD 1150 In-stock
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Sarilumab Related Antibodies

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Description

Sarilumab (Anti-Human IL6Rα, Human Antibody) is a human immunoglobulin G1 monoclonal antibody. Sarilumab, a interleukin-6 (IL-6) receptor antagonist, binds to the IL-6 receptor with high affinity and inhibits cis and trans signaling by IL-6, resulting in reduced inflammation. Sarilumab can be used for the research of Rheumatoid arthritis[1][2].

IC50 & Target[1]

IL-6

 

Clinical Trial
Appearance

Liquid

Color

Colorless to light yellow

SMILES

[Sarilumab]
Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation

Purity: 98.36%

COA (291 KB)

Handling Instructions (2659 KB)
References
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Sarilumab Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SarilumabAnti-Human IL6Rα, Human AntibodyInterleukin RelatedILhumanmonoclonalantibodyrheumatoidarthritisautoinflammatorysignalingInhibitorinhibitorinhibit

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