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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
27 Results for "
Immunoregulatory
" in MedChemExpress (MCE) Product Catalog:
Products (27)
27 Results for "Immunoregulatory" in MCE Product Catalog:
1
Category:
Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology
Target:
1
1 Cited Publications
Cat. No.: HY-P72428
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V‑Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7‑H5; PD‑1H; Dies1; GI24; B7H5; V‑Type Immunoglobulin Domain‑Containing Suppressor Of T‑Cell Activation; V‑Set Domain‑Containing Immunoregulatory Receptor; V‑Domain Ig Suppressor Of T Cell Ac
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70246
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FTH1; Proliferation-Inducing Protein 15; Prev. FTHL6; Ferritin, Heavy Polypeptide 1; FTH; Ferritin H Subunit; Ferritin Heavy Chain; Apoferritin; PIG15; H-Ferritin; PLIF; Ferritin; FHC; NBIA9; Cell Proliferation-Inducing Gene 15 Protein; HFE5; Ferritin Heavy Chain 1; Placenta Immunoregulatory Factor
Species:
Human
Source:
E. coli
Cat. No.: HY-N0204
CAS No.: 129724-84-1
Synonyms: Anemoside A3
Cat. No.: HY-N7700
CAS No.: 15769-56-9
Synonyms: G2013
Target:
Research Areas:
Guluronic acid (G2013) is an orally active oxidative stress regulator and anti-inflammatory agent that exerts pharmacological effects by down-regulating various pro-inflammatory and oxidative stress-related genes (such as TLR4, NF-κB, iNOS, etc.) and inhibiting the activities of COX-2, MMPs and VEGF. Low-dose Guluronic acid up-regulates the expression of immunoregulatory genes SHIP1 and SOCS1, thereby effectively inhibiting cancer-related inflammation, tumor angiogenesis, cell adhesion and metastasis, while reducing the accumulation of immunosuppressive cells. Guluronic acid significantly prolongs the survival time of tumor-bearing hosts within a concentration range without direct cytotoxicity, demonstrating favorable safety. Guluronic acid has involved in the research of multiple sclerosis, ankylosing spondylitis, breast cancer and other inflammatory diseases .
Cat. No.: HY-W145481A
CAS No.: 11078-30-1
Synonyms: Carob galactomannan
Cat. No.: HY-P5724
Cat. No.: HY-175702
Target:
Research Areas:
PD-1/PD-L1-IN-57 (Compound J29) is a PD-1/PD-L1 inhibitor with an IC50 of 5.5 nM. PD-1/PD-L1-IN-57 has a strong immunoregulatory activity, effectively promotes T-cell proliferation and restores the killing ability of tumor cells. PD-1/PD-L1-IN-57 can be used for tumor immunotherapy research .
Cat. No.: HY-P991606
Research Areas:
Cat. No.: HY-174639
Target:
Research Areas:
Human IL13 mRNA encodes the human interleukin 13 (IL13) protein, an immunoregulatory cytokine produced primarily by activated Th2 cells. IL13 is involved in several stages of B-cell maturation and differentiation and is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
Cat. No.: HY-P990736
CAS No.: 2760549-52-6
Synonyms: XTX-202
Target:
Research Areas:
Cat. No.: HY-121856
CAS No.: 36740-73-5
Target:
Research Areas:
Flumizole, a derivative of substituted 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles, was synthesized and evaluated for its immunoregulatory and anti-inflammatory properties in animal models such as rat adjuvant-induced arthritis and mouse oxazolone-induced contact sensitivity assays. This compound class combines structural elements from flumizole and levamisole, aiming to enhance therapeutic efficacy. Symmetrically substituted 5,6-diaryl compounds with specific alkyl heteroatom or halogen substitutions showed optimal potency in the arthritis model. However, variations in activity were less consistent in the contact sensitivity assay. Flumizole and related compounds demonstrate potential as dual-action agents, targeting inflammation and immune modulation, offering promise for therapeutic development in immune-related disorders .
Cat. No.: HY-130625
CAS No.: 2393983-76-9
Target:
Research Areas:
PD-1/PD-L1-IN 6 (compound A13) is a potent PD-1/PD-L1 interaction inhibitor, with an IC50 of 132.8 nM. PD-1/PD-L1-IN 6 exhibits outstanding immunoregulatory activity. PD-1/PD-L1-IN 6 significantly elevates interferon-γ secretion in a Hep3B/OS-8/hPD-L1 and CD3 T cell co-culture model, without significant toxic effect. PD-1/PD-L1-IN 6 restores the immune response in a T cell-tumor co-culture model .
Cat. No.: HY-P3872
CAS No.: 87713-86-8
Target:
Research Areas:
Cat. No.: HY-P81531
Synonyms: VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing Immunoregulatory receptor; V-set Immunoregulatory receptor
Cat. No.: HY-P81531A
Synonyms: VSIR; PP2135, UNQ730/PRO1412; C10orf54, SISP1; VISTA; V-type immunoglobulin domain-containing suppressor of T-cell activation; Platelet receptor Gi24; Stress-induced secreted protein-1; V-set domain-containing Immunoregulatory receptor; V-set Immunoregulatory receptor
Cat. No.: HY-P70983
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V‑Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7‑H5; PD‑1H; Dies1; GI24; B7H5; V‑Type Immunoglobulin Domain‑Containing Suppressor Of T‑Cell Activation; V‑Set Domain‑Containing Immunoregulatory Receptor; V‑Domain Ig Suppressor Of T Cell Ac
Species:
Human
Source:
HEK293
Cat. No.: HY-P73544
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V‑Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7‑H5; PD‑1H; Dies1; GI24; B7H5; V‑Type Immunoglobulin Domain‑Containing Suppressor Of T‑Cell Activation; V‑Set Domain‑Containing Immunoregulatory Receptor; V‑Domain Ig Suppressor Of T Cell Ac
Species:
Rhesus Macaque
Source:
HEK293
Cat. No.: HY-P73546
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V‑Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7‑H5; PD‑1H; Dies1; GI24; B7H5; V‑Type Immunoglobulin Domain‑Containing Suppressor Of T‑Cell Activation; V‑Set Domain‑Containing Immunoregulatory Receptor; V‑Domain Ig Suppressor Of T Cell Ac
Species:
Rat
Source:
HEK293
Cat. No.: HY-P73547
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: VSIR; V‑Set Immunoregulatory Receptor; C10orf54; SISP1; VISTA; B7‑H5; PD‑1H; Dies1; GI24; B7H5; V‑Type Immunoglobulin Domain‑Containing Suppressor Of T‑Cell Activation; V‑Set Domain‑Containing Immunoregulatory Receptor; V‑Domain Ig Suppressor Of T Cell Ac
Species:
Mouse
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
