1 Result for "

KMS34 cells

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "KMS34 cells" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-129478
CAS No.: 100823-03-8
Purity:  99.55%
Research Areas:  

Cancer

TC11 is a MCL1 degrader and apoptosis inducer. TC11 induces sustained CDK1 activation to phosphorylate and degrade MCL1, activates caspase-3, -8, and -9, inhibits centrosomal-regulatory NPM function to block centrosomal clustering, and triggers apoptosis independent of the cereblon pathway. TC11 blocks tumor cell proliferation in vitro and acts against tumor xenografts in vivo. TC11 can be used for the research of multiple myeloma .
loading...
    loading...