2 Results for "

KRAS(G12D)-CRAF

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "KRAS(G12D)-CRAF" in MCE Product Catalog:

Cat. No.: HY-146243
CAS No.: 2766209-50-9
Purity:  99.58%
Target:  

Ras Apoptosis

Research Areas:  

Cancer

TH-Z835 is a mutant selective KRAS (G12D) inhibitor with an IC50 of 1.6 μM. TH-Z835 inhibits both mantGMPPNP/GPPNP exchange and GPPNP/mantGMPPNP exchange .
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Cat. No.: HY-153663
CAS No.: 2847881-81-4
Target:  

Ras

Research Areas:  

Cancer

TH-Z827 is a selective KRAS G12D inhibitor that exhibits activity against GDP-bound and GMPPNP-bound KRAS G12D, but shows no activity against KRAS (WT) and KRAS G12C. TH-Z827 blocks the KRAS G12D-CRAF interaction with a IC50 value of 42 μM. TH-Z827 can be used for the research of pancreatic cancer .
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