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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
LIV-1
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "LIV-1" in MCE Product Catalog:
Cat. No.: HY-P99683
CAS No.: 1629760-29-7
Synonyms: SGN-LIV1A
Target:
Research Areas:
Ladiratuzumab vedotin (SGN-LIV1A) is a LIV-1 targeting antibody drug conjugate (ADC) (IC50: 5.6 nM for LIV-1). Ladiratuzumab vedotin consists of humanized IgG1 monoclonal antibody, MMAE and a protease-cleavable linker. Ladiratuzumab vedotin can drive immunogenic cell death (ICD) to elicit an immune response. Ladiratuzumab vedotin can be used for research of breast cancer [1] .
Cat. No.: HY-P99682
CAS No.: 1629760-28-6
Synonyms: hLIV22
Target:
Research Areas:
Ladiratuzumab (hLIV22) is a humanized monoclonal antibody against zinc transporter LIV-1/ZIP6. Ladiratuzumab is conjugated to MMAE (HY-15162) via a cleavable dipeptide linker to synthesize an antibody-drug conjugate (ADC) Ladiratuzumab vedotin (HY-P99683). Ladiratuzumab vedotin selectively targets LIV-1 protein overexpressed on the surface of tumor cells, enters cells through antibody-mediated receptor endocytosis, releases MMAE to inhibit microtubule polymerization, and kills adjacent tumor cells with a bystander effect. Ladiratuzumab can be used in the study of solid tumors such as metastatic triple-negative breast cancer (mTNBC) [1] .
Cat. No.: HY-176202
CAS No.: 3080930-77-1
Target:
Research Areas:
TLR7/8 agonist 12-PAB-(PEG4-Me)-Cit-Val-PEG2-amide-C2-MC (compound LIV1-IMC (12) linker-payload) is a linker-payload conjugate, used in the synthesis of antibody-drug conjugates (ADCs).TLR7/8 agonist 12-PAB-(PEG4-Me)-Cit-Val-PEG2-amide-C2-MC contains TLR7/8 agonist (HY-170770) (ADC payload) and a linker (HY-176478) [1].
Cat. No.: HY-181697
CAS No.: 2768037-87-0
Target:
Research Areas:
SDP-LIV1 drug-linker is a drug-linker conjugate formed by the condensation of a linker and a topoisomerase I inhibitor. It can be used for the preparation of ADCs, such as SDP-LIV1.
Cat. No.: HY-P81442A
Synonyms: LIV-1; ZIP-6
Cat. No.: HY-P78807
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1; Solute Carrier Family 39 (Metal Ion Transporter), Member 6; LIV-1 Protein, Estrogen Regulated
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P78748
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1; Solute Carrier Family 39 (Metal Ion Transporter), Member 6; LIV-1 Protein, Estrogen Regulated
Species:
Human
Source:
HEK293
Cat. No.: HY-P78616
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Rat
Source:
Sf9 insect cells
Cat. No.: HY-P700463
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P704764
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Human
Source:
HEK293
Cat. No.: HY-P704805
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Cynomolgus
Source:
HEK293
Cat. No.: HY-P704803
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Rat
Source:
HEK293
Cat. No.: HY-P78569
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Cynomolgus
Source:
Sf9 insect cells
Cat. No.: HY-P78749
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Human
Source:
HEK293
Cat. No.: HY-P78806
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Human
Source:
HEK293
Cat. No.: HY-P704763
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Human
Source:
HEK293
Cat. No.: HY-P705232
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC39A6; Solute Carrier Family 39 (Zinc Transporter), Member 6; Solute Carrier Family 39 Member 6; Estrogen-Regulated Protein LIV-1; ZIP6; ZRT/IRT-Like Protein 6; Zrt- And Irt-Like Protein 6; Zinc Transporter 6; Zinc Transporter ZIP6; ZIP-6; LIV-1; LIV1;
Species:
Human
Source:
HEK293
Cat. No.: HY-RS13237
Target:
Research Areas:
SLC39A6 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC39A6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
