4 Results for "

Lysyl-tRNA synthetase 1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "Lysyl-tRNA synthetase 1" in MCE Product Catalog:

Cat. No.: HY-175304
CAS No.: 3052352-34-5
Target:  

Parasite

Research Areas:  

Infection

DMU371 is a Trypanosoma cruzi lysyl-tRNA synthetase 1 (KRS1) inhibitor (IC50=185 nM). DMU371 is promising for research of infectious diseases .
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Cat. No.: HY-P70840
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: KARS1; LysRS; Prev. KARS; KIAA0070; Prev. DFNB89; CMTRIB; Lysyl-tRNA synthetase; DEAPLE; Lysine--tRNA Ligase; LEPID; KARS2; KRS; Lysine tRNA Ligase; Lysyl-tRNA synthetase 1; Deafness, Autosomal Recessive 89
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P991156
CAS No.: 2994192-38-8

Target:  

Ras

Research Areas:  

Inflammation/Immunology

Rapaprutug is a monoclonal antibody targeting human KARS1 (lysyl-tRNA synthetase 1). Rapaprutug blocks the relevant inflammatory signaling pathways in which KARS1 is involved, reducing the production and release of inflammatory factors. Rapaprutug is promising for research of inflammatory diseases .
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Cat. No.: HY-175305
CAS No.: 3052352-22-1
Target:  

Parasite

Research Areas:  

Infection

DMU759 is a Lysyl-tRNA synthetase 1 (KRS1) inhibitor. DMU759 has potent anti-kinetoplastid activity against Trypanosoma cruzi , Trypanosoma brucei and Leishmania donovani. DMU759 significantly reduces parasitemia in acute Chagas disease mice model. DMU759 can be used for parasitic infection like Chagas disease research .
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