9 Results for "

M. bovis

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "M. bovis" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-N6624
CAS No.: 55084-08-7
Skullcapflavone II, a flavonoid derived from Scutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG .
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Cat. No.: HY-D2919
CAS No.: 2177287-88-4
DMN-Tre is a conjugate of a solvatochromic fluorescent dye and trehalose. DMN-Tre takes advantage of the substrate promiscuity of the endogenous antigen 85 protein complex in mycobacteria to be metabolically integrated into the hydrophobic mycobacterial membrane. Once entering this hydrophobic environment, the linked DMN dye fluorescence is "turned on", enabling specific labeling . DMN-Tre can be used to reflect bacterial metabolic activity and support physiological studies of Mycobacterium tuberculosis .
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Cat. No.: HY-P6312
CAS No.: 183273-40-7
Target:  

MHC

Research Areas:  

Inflammation/Immunology

ESAT6 Epitope is a ESAT6 CD4 + T cell epitope. ESAT6 Epitope binds to MHC class I molecules with an IC50 value of approximately 180 nM. ESAT6 Epitope has weak immunogenicity. ESAT6 Epitope can be used in studies related to pulmonary tuberculosis .
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Cat. No.: HY-P4284
CAS No.: 35172-59-9
Target:  

Proteasome ClpP Bacterial

Research Areas:  

Infection

Z-GGF-CMK is an Antibacterial agent, an inhibitor of the ClpP1P2 serine protease complex (with an IC50 of 50 μM against intracellular ClpP1P2 protease activity in Mycobacterium bovis BCG), and a selective inhibitor of the mycobacterial Proteasome (with an IC50 of 50 μM against the proteasome in M. bovis BCG). Z-GGF-CMK inhibits the growth of mycobacteria. Z-GGF-CMK exhibits cytotoxic activity against liver cancer cells. Z-GGF-CMK can be used in the research of tuberculosis .
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Cat. No.: HY-P2948
CAS No.: 9026-43-1
Synonyms: Ser/Thr protein kinase
Research Areas:  

Infection

Protein serine/threonine kinase (Ser/Thr protein kinase) is a signal transduction molecule. Protein serine/threonine kinase phosphorylates specific residues on target substrates, regulates phosphorylation-dependent signal cascades, modulates cellular processes of mycobacteria, blocks phagosome-lysosome fusion, promotes meiotic maturation of Xenopus laevis (African clawed frog) oocytes, rescues the phenotype of Saccharomyces cerevisiae (budding yeast) CDC5 mutants, and exhibits cell cycle phase-specific kinase activity. Protein serine/threonine kinase maintains a tightly regulated cell cycle expression pattern, and sustains the growth and survival of mycobacteria. Protein serine/threonine kinase can be used in studies related to tuberculosis .
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Cat. No.: HY-N11048
CAS No.: 2209112-96-7
Amycolatopsin A is a 20-membered macrolide, that can be isolated from a strain of the rare actinomycete Amycolatopsis sp. MST‐108494. Amycolatopsin A shows antimycobacterial activity against Mycobacterium bovis (BCG) and M. tuberculosis (H37Rv) with IC50 values of 0.4 µM and 4.4 µM, respectively .
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Cat. No.: HY-N12258
CAS No.: 960622-70-2
Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 µM, respectively .
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Cat. No.: HY-173617
CAS No.: 849616-57-5
Synonyms: SAM002706100
Target:  

Bacterial

Research Areas:  

Infection Inflammation/Immunology

GDI-5755 (SAM002706100), an antibacterial agent by inhibiting ClpP1P2, inhibits the growth of Mtb and M. bovis BCG, the model organism of mycobacteria. GDI-5755 can be used in the research for tuberculosis (TB) .
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Cat. No.: HY-172462
Target:  

Bacterial

Research Areas:  

Infection

Mtb-IN-11 (Compound 1e) is an inhibitor of Mycobacterium tuberculosis salicylate synthase (MbtI), with an IC50 of 11.2 μM. Mtb-IN-11 exhibits good in vitro anti-tuberculosis activity, with a MIC99 of 32 μM against M. bovis BCG. Mtb-IN-11 can be used for the research of tuberculosis .
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