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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
MAA
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "MAA" in MCE Product Catalog:
Cat. No.: HY-P99415
CAS No.: 2098724-83-3
Synonyms: MAA868
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Py-MAA-Val-Cit-PAB-MMAE is a drug-Linker conjugates for ADC, which is composed of MMAE (HY-15162) and Py-MAA-Val-Cit-PAB linked. Py-MAA-Val-Cit-PAB-MMAE can be used to synthesize Zapadcine-3a, which targeting TRAILR2. Zapadcine-3a has broad-spectrum anti-tumor activity, and can specifically kill TRAILR2-positive tumors .
Cat. No.: HY-N12931F
Cat. No.: HY-W007978A
CAS No.: 18531-95-8
Synonyms: S-(-)-2,2-Diamino-1,1-binaphthyl
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(S)-[1,1'-Binaphthalene]-2,2'-diamine (S-(-)-2,2-Diamino-1,1-binaphthyl) is a chiral diamine compound and chiral template for molecularly imprinted polymers applied as chiral stationary phases for HPLC separation of DABN racemates .
Cat. No.: HY-153236
CAS No.: 2504068-37-3
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Py-MAA-Val-Cit-PAB-DX8951 is a purine toxin. Py-MAA-Val-Cit-PAB-DX8951 can be used as an intermediate in the synthesis of antibody-drug conjugates .
Cat. No.: HY-RS08985
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NAA10 Human Pre-designed siRNA Set A contains three designed siRNAs for NAA10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-184073
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Mal-PEG8-CO-Ala-Ala-Asp-MAA is a linker. Mal-PEG8-CO-Ala-Ala-Asp-MAA can be used to synthesize QHL-1618 (HY-176772). QHL-1618 is a tumor microenvironment-activated conjugate. QHL-1618 inhibits tumor growth in various tumor models .
Cat. No.: HY-W017180
CAS No.: 72707-66-5
Synonyms: α-(Bromomethyl)acrylic acid; α-Methylated acrylamide; α-MAA
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2-(Bromomethyl) acrylic acid (α-MAA) is a component of Ibt-DOX (HY-181546) .
Cat. No.: HY-181546
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Ibt-DOX is a BTK inhibitor with an IC50 of 2.89 nM. Ibt-DOX is also a targeted covalent activated chemotherapeutic agent composed of the targeting ligand Ibrutinib (HY-10997), Doxorubicin (DOX) (HY-15142A), α-MAA (HY-W017180), and a linker (HY-Y0892). Ibt-DOX specifically binds to BTK and releases DOX, synergistically achieving BTK inhibition and chemotherapeutic killing, significantly enhancing toxicity against B-cell lymphoma cells and greatly reducing the toxic side effects of DOX on BTK-negative cells. Ibt-DOX can be used in lymphoma-related research .
Cat. No.: HY-W275882
CAS No.: 13179-98-1
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1,6-Dimethoxyhexane is an aliphatic ether that serves as a PROTAC linker and fuel additive. 1,6-Dimethoxyhexane is an orally active testicular toxicant. It has no direct toxicity on its own, but exerts toxicity after oxidative metabolism by liver/testicular microsomes to produce 2-Methoxyacetic Acid (MAA). 1,6-Dimethoxyhexane induces apoptosis/necrosis of pachytene spermatocytes, downregulates the expression of HSP70.2, HSP60 and ERp60/PDI A3, and causes spermatogenic tubule degeneration, testicular/thymic atrophy, a sharp decline in epididymal sperm density, and other effects. 1,6-Dimethoxyhexane can be used in studies related to testicular toxicity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
