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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
MAO-A-IN-5
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "MAO-A-IN-5" in MCE Product Catalog:
Cat. No.: HY-186306
CAS No.: 1898180-94-3
Target:
Research Areas:
MAO-A-IN-5 (compound 4g) is a selective human monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.250 μM against MAO-A. MAO-A-IN-5 competitively inhibits the activity of MAO enzymes, impedes the metabolism of neurotransmitter amines, and potentially reduces hydrogen peroxide produced by the MAO-catalyzed cycle. MAO-A-IN-5 can be used for research on Parkinson's disease and depression .
Cat. No.: HY-157089
Research Areas:
AChE/MAO-B-IN-5 is a dual inhibitor of AChE and MAO-B. AChE/MAO-B-IN-5 can used in study Alzheimer’s disease .
Cat. No.: HY-115986
CAS No.: 849909-77-9
Target:
Research Areas:
MAO-B-IN-5 is a potent, selective and orally active MAO-B inhibitor with an IC50 of 0.204 µM. MAO-B-IN-5 has the potential for the research of Parkinson's disease (PD) .
Cat. No.: HY-106041A
CAS No.: 54403-20-2
Synonyms: CGP 4718A
Research Areas:
Sercloremine hydrochloride (CGP 4718A) is a selective and reversible MAO-A and 5-HT-uptake inhibitor. Sercloremine hydrochloride can be used in the research of depression .
Cat. No.: HY-172460
CAS No.: 1432738-00-5
Research Areas:
AChE/BChE/MAO-B-IN-5 is a multitarget inhibitor of cholinesterases (AChE and BChE) and monoamine oxidase MAO-B with blood–brain barrier permeability. It exhibits IC50 values of 0.24 µM, 6.29 µM, and 0.11 µM against AChE, BChE, and MAO-B, respectively. AChE/BChE/MAO-B-IN-5 shows promise for research in the field of neurodegenerative diseases such as Alzheimer's disease .
Target:
Research Areas:
MAO-A/5-HT2AR-IN-1 (compound I14) is a potent MAO-A and 5-HT2AR dual inhibitor, with IC50 values of 0.004 and 0.014 μM, respectively. MAO-A/5-HT2AR-IN-1 is a potential antidepressant agent .
Cat. No.: HY-146677
CAS No.: 2986222-45-9
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Research Areas:
5-HT6R/MAO-B modulator 1 (compound 48) is an antagonist of 5-HT6R at Gs signaling and an irreversible MAO-B inhibitor. 5-HT6R/MAO-B modulator 1 exhibits glioprotective properties. 5-HT6R/MAO-B modulator 1 can reverse Scopolamine-induced memory deficits . 5-HT6R/MAO-B modulator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Cat. No.: HY-N18471
CAS No.: 31363-74-3
Synonyms: 5,7-DHP
Category:
Target:
Cat. No.: HY-N18471A
CAS No.: 1841081-30-8
Synonyms: 5,7-DHP hydrobromide
Target:
Research Areas:
5,7-Dihydroxytryptamine (5,7-DHT) hydrobromide is an autofluorescent (Ex ≈ 365 nm), selective neurotoxin and a transport substrate for MAO-A and 5-HT. 5,7-Dihydroxytryptamine hydrobromide can specifically target and damage central and peripheral 5-HTergic neurons, while affecting 5-HT-related pathways and neurotransmitter balance. 5,7-Dihydroxytryptamine hydrobromide can be used to establish 5-HTergic neuron injury models for studies on neural development, neurodegenerative diseases, as well as mechanisms related to platelet function and retinal neurons .
Cat. No.: HY-N18471B
CAS No.: 39929-27-6
Synonyms: 5,7-DHP creatININe sulfate
Target:
Research Areas:
5,7-Dihydroxytryptamine creatinine sulfate (5,7-DHT) is an autofluorescent (Ex ≈ 365 nm), selective neurotoxin and a transport substrate for MAO-A and 5-HT. 5,7-Dihydroxytryptamine creatinine sulfate can specifically target and damage central and peripheral 5-HTergic neurons, while affecting 5-HT-related pathways and neurotransmitter balance. 5,7-Dihydroxytryptamine creatinine sulfate can be used to establish 5-HTergic neuron injury models for studies on neural development, neurodegenerative diseases, as well as mechanisms related to platelet function and retinal neurons .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
