MAO-A-IN-5
MAO-A-IN-5 is a selective human monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.250 μM against MAO-A. MAO-A-IN-5 competitively inhibits the activity of MAO enzymes, blocks the metabolism of neurotransmitter amines, and may reduce hydrogen peroxide produced by MAO-catalyzed cycles. MAO-A-IN-5 can be used in the research of depression.
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- CAS No.: 1898180-94-3
- Formule: C16H9ClN2O2
- Masse moléculaire:296.71
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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MAO-A 0.250 μM (IC50) |
MAO-B > 100 μM (IC50) |
MAO-A-IN-5 (0.003-100 μM) potently and selectively inhibits recombinant human MAO-A with an IC50 of 0.250 μM, while exhibiting no measurable inhibition of recombinant human MAO-B at concentrations up to 100 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:
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Concentration:
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Incubation Time:
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Result:
| Species | Dose | Route | T1/2 (Distribution) |
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| Macaques[2] | 1 mg/kg | i.p. | 1 μg/L |
Chemical Information
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CAS No. 1898180-94-3
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Masse moléculaire 296.71
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Formule C16H9ClN2O2
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SMILES
ClC1=C(C2=CC=CC=C2)NC3=CC4=C(C(NC4=O)=O)C=C31
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAO-A-IN-5 Related Classifications
HY-186306 Related Classifications
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