4 Results for "

MHV68

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "MHV68" in MCE Product Catalog:

11
Angelicin
Angelicin
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11 Cited Publications
Cat. No.: HY-N0763
CAS No.: 523-50-2
Synonyms: Isopsoralen
Category:  

Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants Disease Research Fields Cancer

Target:  

Apoptosis Virus Protease NF-κB p38 MAPK JNK Caspase

Angelicin is a furanocoumarin compound that functions as an inhibitor of NF-κB and MAPK signaling pathways, exhibiting anti-inflammatory, antiviral, and antitumor activities. It suppresses the lytic replication of γ-herpesviruses, such as MHV-68, early during viral infection, potentially inhibiting RTA gene expression (IC50=28.95 μM). Angelicin also mitigates inflammation by inhibiting the phosphorylation and nuclear translocation of NF-κB, and the phosphorylation of p38 and JNK. Furthermore, it induces apoptosis in neuroblastoma cells by downregulating anti-apoptotic proteins like Bcl-2, Bcl-xL, and Mcl-1, while activating caspase-9 and caspase-3.
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O-Desmethylangolensin (Standard)
O-Desmethylangolensin (Standard)
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Cat. No.: HY-N4075R
CAS No.: 21255-69-6
Category:  

Human Gut Microbiota Metabolites Microorganisms Phenols Polyphenols Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

20(R)-Ginsenoside Rh2 (Standard) is the analytical standard of 20(R)-Ginsenoside Rh2. This product is intended for research and analytical applications. 20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity . 20(R)-Ginsenoside Rh2 inhibits the replication and proliferation of mouse and human gammaherpesvirus 68 (MHV-68) with an IC50 of 2.77 μM for murine MHV-68 .
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Angelicin (Standard)
Angelicin (Standard)
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Cat. No.: HY-N0763R
CAS No.: 523-50-2
Synonyms: Isopsoralen (Standard)
Category:  

Leguminosae Coumarins Psoralea corylifolia L. Phenylpropanoids Plants

Target:  

Reference Standards Apoptosis Virus Protease

Angelicin (Standard) is the analytical standard of Angelicin. This product is intended for research and analytical applications. Angelicin is a natural tricyclic aromatic hydrocarbon compound that is structurally related to psoralen and has anti-cancer, anti-inflammatory, anti-viral and other activities. Cytotoxic, IC50: 49.56 μM; inhibits MHV-68, IC50: 5.39 μg/ml (28.95 μM).
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Anti-Mouse Vβ4 TCR Antibody (KT4)
Anti-Mouse Vβ4 TCR Antibody (KT4)
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Cat. No.: HY-P990142

Target:  

MHC

Research Areas:  

Infection Inflammation/Immunology

Anti-Mouse Vβ4 TCR Antibody (KT4) is an anti-mouse Vβ4 TCR IgG2b monoclonal antibody. Anti-Mouse Vβ4 TCR Antibody (KT4) can reduce the proportion of Vβ4 + T cells without affecting their function. Anti-Mouse Vβ4 TCR Antibody (KT4) can be used for research on immunology and infection conditions such as virus infection. Anti-Mouse Vβ4 TCR Antibody (KT4) is often used in flow cytometry .
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