2 Results for "

MKK3/6 Inhibitors

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "MKK3/6 Inhibitors" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-119917
CAS No.: 489-35-0
Purity:  ≥99.0%
Gossypetin is a hexahydroxylated flavonoid and is a potent mitogen-activated protein kinase kinase (MKK)3 and MKK6 inhibitor with strongly attenuates the MKK3/6-p38 signaling pathway, has various pharmacological activities, including antioxidant, antibacterial and anticancer activities .
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Cat. No.: HY-N0811
CAS No.: 139051-27-7
Anemarsaponin B is a steroidal saponin. Anemarsaponin B decreases the protein and mRNA levels of iNOS and COX-2. Anemarsaponin B reduces the expressions and productions of pro-inflammatory cytokines, including TNF-a and IL-6. Anemarsaponin B inhibits the nuclear translocation of the p65 subunit of NF-κB by blocking the phosphorylation of IκBα. Anemarsaponin B also inhibits the phosphorylation of MAP kinase kinases 3/6 (MKK3/6) and mixed lineage kinase 3 (MLK3). Anti-inflammatory effect .
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