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Results for "

MMP-13-IN-1

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

2

Natural
Products

Art. -Nr. Produktname Target Forschungsgebiete Chemical Structure
  • HY-N1463
    Luteolin 7-O-glucuronide
    3 Publications Verification

    LuteolIN 7-glucuronide

    		 MMP Neurological Disease Inflammation/Immunology
    Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively .
    Luteolin 7-O-glucuronide
  • HY-W011085
    CP-471474
    1 Publications Verification

    		 MMP Inflammation/Immunology
    CP-471474 is an orally active and pan MMP inhibitor, with IC50 values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively .
    CP-471474
  • HY-117970
    MMPI-1154

    		MMP Cardiovascular Disease
    MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC50=6.6 μM) and can be used for the study of acute myocardial infarction. MMPI-1154 also inhibits the activity of MMP-13, MMP-1 and MMP-9 with IC50s of 1.8 μM,10 μM, and 13 μM, respectively .
    MMPI-1154
  • HY-154868
    MMP-13-IN-1

    		MMP Cardiovascular Disease Cancer
    MMP-13-IN-1 is a potent and selective inhibitor of MMP-13 with a IC50 value of 16 nM. MMP-13-in-1 can be used for atherosclerosis research .
    MMP-13-IN-1
  • HY-112160
    XL-784 free base

    		MMP Cardiovascular Disease
    XL-784 free base is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9 and MMP-13, respectively .
    XL-784 free base
  • HY-N1463R
    Luteolin 7-O-glucuronide (Standard)

    LuteolIN 7-glucuronide (Standard)

    		 Reference Standards MMP Neurological Disease Inflammation/Immunology
    Luteolin 7-O-glucuronide (Standard) is the analytical standard of Luteolin 7-O-glucuronide. This product is intended for research and analytical applications. Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively .
    Luteolin 7-O-glucuronide (Standard)
  • HY-114396
    BR351

    		MMP Cancer
    BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively .
    BR351
  • HY-43586
    BR351 precursor

    		MMP Cancer
    BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively .
    BR351 precursor
  • HY-119138
    R-130823

    		p38 MAPK MMP PGE synthase Inflammation/Immunology
    R-130823 is an orally active, highly selective p38α inhibitor with an IC50 of 22 nM against p38α, an IC50 of 820 nM against p38β, and no activity against p38γ or p38δ. R-130823 downregulates downstream cartilage degradation and inflammatory mediators, and inhibits the release of MMP-13, MMP-1 and PGE2. R-130823 reduces hind paw swelling, improves hyperalgesia, and blocks arthritis progression. R-130823 is applicable to research related to osteoarthritis and rheumatoid arthritis .
    R-130823

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