1. Metabolic Enzyme/Protease
  2. MMP
  3. BR351

BR351 

Cat. No.: HY-114396
Handling Instructions

BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively.

For research use only. We do not sell to patients.

BR351 Chemical Structure

BR351 Chemical Structure

CAS No. : 960113-85-3

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Description

BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively[1].

IC50 & Target

MMP-9

11 nM (IC50)

MMP-2

4 nM (IC50)

MMP-8

2 nM (IC50)

MMP13

50 nM (IC50)

Molecular Weight

424.49

Formula

C₂₀H₂₅FN₂O₅S

CAS No.

960113-85-3

SMILES

CC(C)[[email protected]@H](N(S(=O)(C1=CC=C(OCCF)C=C1)=O)CC2=CC=CC=C2)C(NO)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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BR351
Cat. No.:
HY-114396
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