1. Metabolic Enzyme/Protease
  2. MMP

BR351 

Cat. No.: HY-114396
Handling Instructions

BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively.

For research use only. We do not sell to patients.

BR351 Chemical Structure

BR351 Chemical Structure

CAS No. : 960113-85-3

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  • Biological Activity

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Description

BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively[1].

IC50 & Target

MMP-9

11 nM (IC50)

MMP-2

4 nM (IC50)

MMP-8

2 nM (IC50)

MMP13

50 nM (IC50)

References
Molecular Weight

424.49

Formula

C₂₀H₂₅FN₂O₅S

CAS No.

960113-85-3

SMILES

CC(C)[[email protected]@H](N(S(=O)(C1=CC=C(OCCF)C=C1)=O)CC2=CC=CC=C2)C(NO)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

Product Name:
BR351
Cat. No.:
HY-114396
Quantity:

BR351

Cat. No.: HY-114396