960113-85-3
960113-85-3
Chemical Structure
BR351
- CAS 番号: 960113-85-3
- Formula:C20H25FN2O5S
- Molecular Weight:424.49
IUPAC Name: (R)-2-((N-benzyl-4-(2-fluoroethoxy)phenyl)sulfonamido)-N-hydroxy-3-methylbutanamide
InChIKey: NSDMBIOAMTZMED-LJQANCHMSA-N
SMILES: CC(C)[C@@H](N(S(=O)(C1=CC=C(OCCF)C=C1)=O)CC2=CC=CC=C2)C(NO)=O
Biological Activity: BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively[1].
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BR351 | BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively. | |||||||||||||||||||||
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References
Keywords
