210755-45-6
210755-45-6
Chemical Structure
CP-471474
- CAS No.: 210755-45-6
- Formula:C16H17FN2O5S
- Molecular Weight:368.38
IUPAC Name: 2-((4-(4-fluorophenoxy)phenyl)sulfonamido)-N-hydroxy-2-methylpropanamide
InChIKey: QCOQJYRPDUMCNP-UHFFFAOYSA-N
SMILES: CC(C)(NS(=O)(C1=CC=C(OC2=CC=C(F)C=C2)C=C1)=O)C(NO)=O
Biological Activity: CP-471474 is an orally active and pan MMP inhibitor, with IC50 values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CP-471474 | 99.2% | CP-471474 is an orally active and pan MMP inhibitor, with IC50 values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively. | ||||||||||||||||||||
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References
- [1]. L E Rohde, et al. Matrix metalloproteinase inhibition attenuates early left ventricular enlargement after experimental myocardial infarction in mice. Circulation. 1999 Jun 15;99(23):3063-70. [Content Brief]
- [2]. Moisés Selman, et al. Matrix metalloproteinases inhibition attenuates tobacco smoke-induced emphysema in Guinea pigs. Chest. 2003 May;123(5):1633-41. [Content Brief]
Keywords
