Hit 14
Hit 14 is an inhibitor for C-X-C chemokine receptor type 4 (CXCR4) with IC50 of 254 nM. Hit 14 inhibits the migration and invasion of cell MDA-MB-231. Hit 14 inhibits the Akt phosphorylation, exhibits anti-inflammatory activity, and ameliorateds the ear swelling and damage in mouse models.
For research use only. We do not sell to patients.
- CAS No.: 440338-68-1
- Formula: C22H28N2O7S2
- Molecular Weight:496.60
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
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Help & FAQs
Biological Activity
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12G5 mAb-CXCR4 254 nM (IC50) |
Chemical Information
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CAS No. 440338-68-1
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Appearance Solid
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Molecular Weight 496.60
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Formula C22H28N2O7S2
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Color White to off-white
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SMILES
O=S(C1=CC=C(OC2=CC=C(S(=O)(NCC3OCCC3)=O)C=C2)C=C1)(NCC4OCCC4)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (240 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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