1. Metabolic Enzyme/Protease
  2. MMP

BR351 precursor 

Cat. No.: HY-43586
Handling Instructions

BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively. Potential tools for the molecular imaging of activated MMPs with PET.

For research use only. We do not sell to patients.

BR351 precursor Chemical Structure

BR351 precursor Chemical Structure

CAS No. : 960113-89-7

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Description

BR351 precursor is a precursor of BR351. BR351 is a brain penetrant MMP inhibitor with IC50s of 4, 2, 11, 50 nM for MMP2, MMP8, MMP9 and MMP13, respectively[1]. Potential tools for the molecular imaging of activated MMPs with PET[2].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7341 mL 8.6703 mL 17.3406 mL
5 mM 0.3468 mL 1.7341 mL 3.4681 mL
10 mM 0.1734 mL 0.8670 mL 1.7341 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

576.68

Formula

C₂₇H₃₂N₂O₈S₂

CAS No.

960113-89-7

SMILES

CC(C)[[email protected]@H](N(S(=O)(C1=CC=C(OCCOS(=O)(C2=CC=C(C)C=C2)=O)C=C1)=O)CC3=CC=CC=C3)C(NO)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
BR351 precursor
Cat. No.:
HY-43586
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BR351 precursor

Cat. No.: HY-43586