3 Results for "

Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA" in MCE Product Catalog:

Cat. No.: HY-P4931A
CAS No.: 1392300-20-7
Target:  

Fluorescent Dye

Research Areas:  

Others

Mca-KPLGL-Dap(Dnp)-AR-NH2 TFA is a fluorogenic substrate for matrix metalloproteinases (MMPs). 7-methoxycoumarin-4 acetyl (Mac) is released and its fluorescence can be used to quantify MMP activity. Mac displays Ex/Em of 328/420 nm .
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2
2 Cited Publications
Cat. No.: HY-P4931
CAS No.: 720710-69-0
Target:  

MMP

Research Areas:  

Cancer

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)
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Cat. No.: HY-131498
CAS No.: 140430-53-1
Purity:  99.67%
Synonyms: Mca-Pro-Leu-Gly-Leu-Dpa-Ala-ARg-NH2
Target:  

Fluorescent Dye MMP

Research Areas:  

Cancer

MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n
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