10 Results for "

Microphthalmia Associated Transcription Factor (MITF)

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Microphthalmia Associated Transcription Factor (MITF)" in MCE Product Catalog:

Cat. No.: HY-N1481
CAS No.: 112-63-0
Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins .
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Cat. No.: HY-N6901
CAS No.: 56857-57-9
Luteolin 7-sulfate is isolated from Phyllospadix iwatensis Makino, a marine plant. Luteolin 7-sulfate attenuates TYR gene expression through the intervention of a cAMP-responsive element binding protein (CREB)- and microphthalmia-associated transcription factor (MITF)-mediated signaling pathway, leading to the decreased melanin synthesis .
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Cat. No.: HY-N10623
CAS No.: 2767066-84-0
5-epi-Arvestonate A is a sesquiterpenoid isolated from the whole plants of Seriphidium transiliense. 5-epi-Arvestonate A promotes melanogenic production by activating the transcription of microphthalmia-associated transcription factor (MITF) and tyrosinase family genes. 5-epi-Arvestonate A inhibits the expression of IFN-γ-chemokine through the JAK/STAT signaling pathway in immortalized human keratinocyte (HaCaT) cells .
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Cat. No.: HY-P4497
CAS No.: 71835-80-8
Target:  

ERK

Research Areas:  

Cancer

Prolylserine, a dipeptide, is an inhibitor of melanogenesis production in Mel-Ab cells. Prolylserine decreases expression of microphthalmia-associated transcription factor (MITF) and tyrosinase, induces phorphosylation of ERK, but not cAMP response element binding protein (CREB) .
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Cat. No.: HY-N1481R
CAS No.: 112-63-0
Methyl linoleate (Standard) is the analytical standard of Methyl linoleate. This product is intended for research and analytical applications. Methyl linoleate, a major active constituent of Sageretia thea fruit (HFSF), is a major anti-melanogenic compound. Methyl linoleate downregulates microphthalmia-associated transcription factor (MITF) and tyrosinase-related proteins .
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Cat. No.: HY-120996
CAS No.: 321744-58-5
Purity:  99.90%
Synonyms: trans-10-Pentadecenoic acid
10 (E)-Pentadecenoic acid (trans-10-Pentadecenoic acid) is a melanin synthesis inhibitor. 10 (E)-Pentadecenoic acid inhibits nuclear translocation and reduces the protein level of phosphorylated microphthalmia-associated transcription factor (MITF), as well as decreases intracellular tyrosinase activity. 10 (E)-Pentadecenoic acid can be used in the research of skin pigmentation disorders .
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Cat. No.: HY-157010
CAS No.: 1365531-21-0
Target:  

Tyrosinase PKA

Research Areas:  

Others

AP736 is a potent tyrosinase inhibitor (IC50 = 0.9 μM) with anti-melanogenesis activity in normal human melanocytes (IC50 = 0.11 μM). AP736 suppresses the expression of tyrosinase and TRP-1/2 by inhibiting the cAMP-PKA-CREB signalling axis, leading to reduced microphthalmia-associated transcription factor (MITF) transcripts and proteins. AP736 can be used for melanogenesis and hyperpigmentation research .
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Cat. No.: HY-N3810
CAS No.: 57719-81-0
ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid is an anti-melanin synthesis tyrosinase inhibitor, which can be isolated from Pteris fern. ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid regulates the melanogenesis transcription factor microphthalmia-associated transcription factor (MITF). The 11α-OH, 15-oxo and 16-en moieties of ent-11α-Hydroxy-15-oxokaur-16-en-19-oic acid are key fragments that inhibit melanin synthesis. The 19-COOH moiety has been implicated in the inhibition of cytotoxicity associated with 11α-OH KA and related compounds .
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Cat. No.: HY-P86614
Synonyms: MITF; BHLHE32; Microphthalmia-Associated Transcription Factor; Class E basic helix-loop-helix protein 32; bHLHe32

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P810742
Synonyms: BHLHE32, MITF, Microphthalmia-Associated Transcription Factor, Class E basic helix-loop-helix protein 32, bHLHe32

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human, Mouse, Rat

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