Prolylserine
Prolylserine, a dipeptide, is an inhibitor of melanogenesis production in Mel-Ab cells. Prolylserine decreases expression of microphthalmia-associated transcription factor (MITF) and tyrosinase, induces phorphosylation of ERK, but not cAMP response element binding protein (CREB).
For research use only. We do not sell to patients.
- CAS No.: 71835-80-8
- Formula: C8H14N2O4
- Molecular Weight:202.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MDCK | EC50 |
1.6 mM
Compound: 64
|
Activation of human PEPT1 expressed in MDCK cells
Activation of human PEPT1 expressed in MDCK cells
|
[PMID: 16759105] |
| MDCK | IC50 |
>16 mM
Compound: 64
|
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
Binding affinity to human PEPT1 assessed as inhibition of [14C]Gly-Sar uptake in MDCK cells
|
[PMID: 16759105] |
Chemical Information
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CAS No. 71835-80-8
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Molecular Weight 202.21
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Formula C8H14N2O4
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Sequence
H-Pro-Ser-OH
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Sequence Shortening
PS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)