2. Search Result
Search Result
Results for "

Mycobacterium avium

" in MedChemExpress (MCE) Product Catalog:

18

Inhibitors & Agonists

4

Biochemical Assay Reagents

1

Inhibitory Antibodies

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D1005A8
    Poloxamer 181 (L61)

    PEG-PPG-PEG, 2000 (Average)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial P-glycoprotein Infection Cancer
    Poloxamer 181 L61 is a block polymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 2000. Poloxamer has the ability to inhibit P-gp. Poloxamer 181 has antimicrobial activity and can inhibit Mycobacterium avium. Poloxamer 181 can form a thermally reversible hydrogel and is used as a food additive, and as an agent delivery carrier in cosmetics, pharmaceuticals and tissue engineering .
    Poloxamer 181 (L61)
  • HY-D1005A10
    Poloxamer 184 (L64)

    PEG-PPG-PEG, 2900 (Average)

    		 Environmental Pollutants Biochemical Assay Reagents Bacterial P-glycoprotein Infection Inflammation/Immunology
    Poloxamer 184 L64 is a block copolymer of polyethylene oxide and polypropylene oxide with an average molecular weight of 2900. Poloxamer has the ability to inhibit P-gp. Poloxamer 184 exhibits short-term skin toxicity, characterized by mild erythema and intradermal inflammatory reactions. Poloxamer 184 has antimicrobial activity, inhibiting 60% of Mycobacterium avium at a concentration of 1 mg/mL. Poloxamer 184 forms a thermoreversible hydrogel and is used as a food additive and as a drug delivery carrier in cosmetics and tissue engineering .
    Poloxamer 184 (L64)
  • HY-N1673
    2,5-Dihydroxybenzaldehyde

    Gentisaldehyde

    		 Bacterial Infection
    2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC50 of 500 mg/L .
    2,5-Dihydroxybenzaldehyde
  • HY-113784
    Thiocarlide

    Isoxyl

    		 Antibiotic Bacterial Infection
    Thiocarlide is a potent antibacterial agent. Thiocarlide inhibits Mycobacterium tuberculosis H37Rv, Mycobacterium bovisBCG, Mycobacterium avium, and Mycobacterium aurum A+ with MICs of 2.5, 0.5, 2.0 and 2.0 μg/mL, respectively .
    Thiocarlide
  • HY-D1005A9
    Poloxamer 183 (L63)

    PEG-PPG-PEG, 2650 (Average)

    		 Biochemical Assay Reagents Bacterial P-glycoprotein Infection
    Poloxamer 183 L63 is a block copolymer of polyoxyethylene and polyoxypropylene with an average molecular weight of 2000. Poloxamer has the ability to inhibit P-gp. Poloxamer 183 exhibits antimicrobial activity and can inhibit Mycobacterium avium. Poloxamer 183 can be used as a cosmetic ingredient .
    Poloxamer 183 (L63)
  • HY-D1005A4
    Poloxamer 122 (L42)

    PEG-PPG-PEG, 1630 (Average)

    		 Biochemical Assay Reagents Bacterial Infection
    Poloxamer 122 L42 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 1630. Poloxamer 122 L42 exhibits antimicrobial activity, that inihibits 56% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 122 L42 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
    Poloxamer 122 (L42)
  • HY-113729
    B 746

    		Bacterial Infection
    B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin .
    B 746
  • HY-19814
    Toripristone

    RU-40555

    		 Glucocorticoid Receptor Infection Inflammation/Immunology
    Toripristone (RU-40555) is a cortisol receptor inhibitor. Toripristone combined with clarithromycin can increase the antibacterial activity of Mycobacterium avium complex infection .
    Toripristone
  • HY-135285
    Rifamexil

    		Antibiotic Bacterial Infection
    Rifamexil is an antibiotic Rifamycin (HY-B1907A) derivative that is active against Mycobacterium avium complex and other mycobacteria .
    Rifamexil
  • HY-173355
    RCB18350

    		Bacterial Infection
    RCB18350 is an antituberculosis agent that belongs to the class of isoxazole derivatives. RCB18350 has bacteriostatic activity and inhibits the growth of Mycobacterium tuberculosis with an MIC of 1.25 μg/mL. RCB18350 is effective against multidrug-resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, slow-growing mycobacteria such as Mycobacterium bovis BCG and Mycobacterium avium .
    RCB18350
  • HY-113834
    (R,R)-Ethambutol

    		Bacterial Infection
    (R,R)-Ethambutol is an antituberculosis compound with tuberculosis inhibitory activity. (R,R)-Ethambutol is often used in combination with other antituberculosis compounds to enhance the efficacy. (R,R)-Ethambutol can also be used to inhibit Mycobacterium avium complex infection and Mycobacterium kansasii infection .
    (R,R)-Ethambutol
  • HY-N12823
    Caprazene

    		Bacterial Metabolic Disease
    Caprazene is an antimycobacterial compound and precursor molecule for semi-synthetic antibacterial antibiotics, used for studies on tuberculosis and Mycobacterium avium complex infections, which can be isolated from the acid-treated caprazamycin (CPZ) A-G mixture .
    Caprazene
  • HY-159899
    DHFR-IN-22

    		Bacterial Antibiotic Dihydrofolate reductase (DHFR)
    DHFR-IN-22 (Compound 8) is a DHFR (Dihydrofolate Reductase) inhibitor belonging to the class of 2,4-diaminopyrimidine compounds. DHFR-IN-22 exhibits significant inhibitory activity against purified DHFR enzyme and major species of nontuberculous mycobacteria (NTM), namely Mycobacterium avium and Mycobacterium abscessus. It shows an IC50 of 1.1 nM and MIC of 1.5 μg/mL against M. abscessus, and an IC50 of 6.3 nM and MIC of 0.1 μg/mL against M. avium. Additionally, it demonstrates an IC50 of 2100 nM against human DHFR. DHFR-IN-22 holds potential for studying novel strategies to combat NTM infections .
    DHFR-IN-22
  • HY-N1673R
    2,5-Dihydroxybenzaldehyde (Standard)

    Gentisaldehyde (Standard)

    		 Reference Standards Bacterial Infection
    2,5-Dihydroxybenzaldehyde (Standard) is the analytical standard of 2,5-Dihydroxybenzaldehyde. This product is intended for research and analytical applications. 2,5-Dihydroxybenzaldehyde (Gentisaldehyde) is a naturally occurring antimicrobial that inhibits the growth of Mycobacterium avium subsp. paratuberculosis. 2,5-Dihydroxybenzaldehyde is active against S. aureus strains with a MIC50 of 500 mg/L[1][2].
    2,5-Dihydroxybenzaldehyde (Standard)
  • HY-106422
    EDP-420

    EP-013420; S-013420

    		 Bacterial Infection Inflammation/Immunology
    EDP-420 (EP-013420; S-013420) is an orally active antibacterial agent. EDP-420 inhibits the Mycobacterium avium complex (MAC) in macrophages. EDP-420 reduces bacterial counts in a mouse model of macrolide infection. EDP-420 inhibits pneumococcal activity in a rabbit model of meningitis. EDP-420 can be used in research on inflammatory infectious diseases such as meningitis .
    EDP-420
  • HY-P991760
    Anti-IL-10 Antibody (JES3-19F1)

    		Interleukin Related Inflammation/Immunology
    Anti-IL-10 Antibody (JES3-19F1) reacts with human IL-10, and is a capture or coating antibody in ELISA applications. Anti-IL-10 Antibody (JES3-19F1) reduces bacterial load in Mycobacterium avium infected mice. Recommend Isotype Controls: Rat IgG2a kappa, Isotype Control (HY-P990679) .
    Anti-IL-10 Antibody (JES3-19F1)
  • HY-181286
    ETX1975-3

    		Cytochrome P450 Infection
    ETX1975-3 is an orally active inhibitor and bactericide targeting the bd cytochrome oxidase of Mycobacterium tuberculosis. ETX1975-3 disrupts electron transfer between the b-heme centers of the target enzyme, and in combination with Q203 (HY-101040), exerts bactericidal activity against both replicating and non-replicating Mycobacterium tuberculosis, and reduces bacterial loads in acute mouse models. ETX1975-3 retains activity against clinical isolates of multidrug-resistant/extensively drug-resistant Mycobacterium tuberculosis and non-tuberculous mycobacteria, while possessing favorable preclinical ADMET properties. ETX1975-3 can be used in studies related to tuberculosis and non-tuberculous mycobacterial infections .
    ETX1975-3
  • HY-124195
    Antitubercular agent-57

    		Bacterial Infection
    Antitubercular agent-57 is a selective antimycobacterial agent with low in vitro toxicity against mammalian cell lines including hepatocyte cell lines. Antitubercular agent-57 exhibits activity against drug-sensitive, multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains, and shows no cross-resistance with first-line or second-line antitubercular agents. Antitubercular agent-57 has no activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. Antitubercular agent-57 can be used in the research of tuberculosis and multidrug-resistant tuberculosis .
    Antitubercular agent-57

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: