Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Mycobacterium avium
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Mycobacterium avium" in MCE Product Catalog:
Cat. No.: HY-D1005A8
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 2000 (Average)
Cat. No.: HY-D1005A10
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 2900 (Average)
Category:
Infection Microorganisms Ketones, Aldehydes, Acids Phenols Polyphenols Disease Research Fields
Target:
Target:
Research Areas:
Thiocarlide is a potent antibacterial agent. Thiocarlide inhibits Mycobacterium tuberculosis H37Rv, Mycobacterium bovisBCG, Mycobacterium avium, and Mycobacterium aurum A+ with MICs of 2.5, 0.5, 2.0 and 2.0 μg/mL, respectively .
Cat. No.: HY-D1005A9
CAS No.: 9003-11-6
Synonyms: PEG-PPG-PEG, 2650 (Average)
Cat. No.: HY-19814
CAS No.: 91935-26-1
Synonyms: RU-40555
Target:
Research Areas:
Toripristone (RU-40555) is a cortisol receptor inhibitor. Toripristone combined with clarithromycin can increase the antibacterial activity of Mycobacterium avium complex infection .
Cat. No.: HY-135285
CAS No.: 113102-19-5
Target:
Research Areas:
Rifamexil is an antibiotic Rifamycin (HY-B1907A) derivative that is active against Mycobacterium avium complex and other mycobacteria .
Cat. No.: HY-173355
CAS No.: 3052630-27-7
RCB18350 is an antituberculosis agent that belongs to the class of isoxazole derivatives. RCB18350 has bacteriostatic activity and inhibits the growth of Mycobacterium tuberculosis with an MIC of 1.25 μg/mL. RCB18350 is effective against multidrug-resistant Mycobacterium tuberculosis (MDR-TB) clinical isolates, slow-growing mycobacteria such as Mycobacterium bovis BCG and Mycobacterium avium .
Cat. No.: HY-113834
CAS No.: 10054-05-4
(R,R)-Ethambutol is an antituberculosis compound with tuberculosis inhibitory activity. (R,R)-Ethambutol is often used in combination with other antituberculosis compounds to enhance the efficacy. (R,R)-Ethambutol can also be used to inhibit Mycobacterium avium complex infection and Mycobacterium kansasii infection .
Cat. No.: HY-N12823
CAS No.: 740805-17-8
Category:
Target:
Cat. No.: HY-159899
CAS No.: 2941327-87-1
DHFR-IN-22 (Compound 8) is a DHFR (Dihydrofolate Reductase) inhibitor belonging to the class of 2,4-diaminopyrimidine compounds. DHFR-IN-22 exhibits significant inhibitory activity against purified DHFR enzyme and major species of nontuberculous mycobacteria (NTM), namely Mycobacterium avium and Mycobacterium abscessus. It shows an IC50 of 1.1 nM and MIC of 1.5 μg/mL against M. abscessus, and an IC50 of 6.3 nM and MIC of 0.1 μg/mL against M. avium. Additionally, it demonstrates an IC50 of 2100 nM against human DHFR. DHFR-IN-22 holds potential for studying novel strategies to combat NTM infections .
Target:
Cat. No.: HY-106422
CAS No.: 736992-12-4
Synonyms: EP-013420; S-013420
Target:
Research Areas:
EDP-420 (EP-013420; S-013420) is an orally active antibacterial agent. EDP-420 inhibits the Mycobacterium avium complex (MAC) in macrophages. EDP-420 reduces bacterial counts in a mouse model of macrolide infection. EDP-420 inhibits pneumococcal activity in a rabbit model of meningitis. EDP-420 can be used in research on inflammatory infectious diseases such as meningitis .
Cat. No.: HY-185308
CAS No.: 895525-81-2
Trisaccharides 3 (compoudn 3) is a GlfT2 acceptor substrate with a 50 μM Ka. Trisaccharides 3 acts as an acceptor substrate for the β-(1→6) galactofuranosyl transferase activity of GlfT2, binds competitively at GlfT2’s single active site pocket, and undergoes galactosylation by GlfT2 with UDP-Galf to form a tetrasaccharide product. Trisaccharides 3 can be used for the research of tuberculosis, hiv-associated Mycobacterium avium infections .
Cat. No.: HY-185668
CAS No.: 162554-02-1
Target:
Research Areas:
2',5'-Dideoxy-3'-ATP is an adenylate cyclase inhibitor. 2',5'-Dideoxy-3'-ATP exerts linear noncompetitive inhibition via binding to the distinct P-site. 2',5'-Dideoxy-3'-ATP binds and stabilizes the dimeric form of Mycobacterium avium adenylyl cyclase Ma1120 to inhibit activity .
Cat. No.: HY-187128
CAS No.: 562817-22-5
Antibacterial agent 362 is a broad-spectrum antibacterial agent. Antibacterial agent 362 exhibits broad-spectrum inhibitory activity against a variety of mycobacteria and Staphylococcus aureus, with a MIC50 of 235 μM against M. tuberculosis, while it shows no activity against Escherichia coli. Antibacterial agent 362 can be used in research related to tuberculosis and mycobacterial infections .
Cat. No.: HY-P991760
Target:
Research Areas:
Cat. No.: HY-181286
Target:
Research Areas:
ETX1975-3 is an orally active inhibitor and bactericide targeting the bd cytochrome oxidase of Mycobacterium tuberculosis. ETX1975-3 disrupts electron transfer between the b-heme centers of the target enzyme, and in combination with Q203 (HY-101040), exerts bactericidal activity against both replicating and non-replicating Mycobacterium tuberculosis, and reduces bacterial loads in acute mouse models. ETX1975-3 retains activity against clinical isolates of multidrug-resistant/extensively drug-resistant Mycobacterium tuberculosis and non-tuberculous mycobacteria, while possessing favorable preclinical ADMET properties. ETX1975-3 can be used in studies related to tuberculosis and non-tuberculous mycobacterial infections .
Cat. No.: HY-124195
CAS No.: 461431-74-3
Antitubercular agent-57 is a selective antimycobacterial agent with low in vitro toxicity against mammalian cell lines including hepatocyte cell lines. Antitubercular agent-57 exhibits activity against drug-sensitive, multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis strains, and shows no cross-resistance with first-line or second-line antitubercular agents. Antitubercular agent-57 has no activity against Gram-positive bacteria, Gram-negative bacteria and fungal strains. Antitubercular agent-57 can be used in the research of tuberculosis and multidrug-resistant tuberculosis .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
