Trisaccharides 3 

Trisaccharides 3 (compoudn 3) is a GlfT2 acceptor substrate with a 50 μM K_a. Trisaccharides 3 acts as an acceptor substrate for the β-(1→6) galactofuranosyl transferase activity of GlfT2, binds competitively at GlfT2’s single active site pocket, and undergoes galactosylation by GlfT2 with UDP-Galf to form a tetrasaccharide product. Trisaccharides 3 can be used for the research of tuberculosis, hiv-associated Mycobacterium avium infections^[1].

Trisaccharides 3 (compoudn 3) (4 mM; 3.2-11.3 mM) binds competitively with trisaccharide 2 to a single active-site pocket of recombinant Mycobacterium tuberculosis GlfT2 enzyme, with a measured dissociation constant (K_d) of 50 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

616.65

C₂₆H₄₈O₁₆

895525-81-2

O[C@@H]1[C@@H](O)[C@H]([C@H](O)CO)O[C@H]1O[C@@H]([C@@H]2O[C@@H](OC[C@H]([C@@H]3O[C@@H](OCCCCCCCC)[C@H](O)[C@H]3O)O)[C@H](O)[C@H]2O)CO

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Szczepina MG, et al. STD-NMR studies suggest that two acceptor substrates for GlfT2, a bifunctional galactofuranosyltransferase required for the biosynthesis of Mycobacterium tuberculosis arabinogalactan, compete for the same binding site. Chembiochem. 2009;10(12):2052-2059.