B 746
B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin.
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- CAS No.: 103051-26-9
- Formule: C26H20Cl2N4
- Masse moléculaire:459.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
In Vitro
B746 (1, 3, 10 μM; 7 days) significantly inhibits the growth of mycobacteria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:beige mice
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Dosage:10, 20, 30 mg/kg
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Administration:p.o.; 10, 20, 30 mg/kg; single dose; first day and 2, 4 and 6 week after infection
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Result:Reduced Colony Forming Units (CFU) counts of Mycobacteria in spleen of beige mice.
Chemical Information
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CAS No. 103051-26-9
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Masse moléculaire 459.37
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Formule C26H20Cl2N4
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SMILES
CC/N=C1C=C2N(C3=C(N=C2C=C\1NC4=CC=C(C=C4)Cl)C=CC=C3)C5=CC=C(C=C5)Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
B 746 Related Classifications
HY-113729 Related Classifications
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