B 746
B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin.
For research use only. We do not sell to patients.
- CAS No.: 103051-26-9
- Formula: C26H20Cl2N4
- Molecular Weight:459.37
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
B746 (1, 3, 10 μM; 7 days) significantly inhibits the growth of mycobacteria[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:beige mice
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Dosage:10, 20, 30 mg/kg
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Administration:p.o.; 10, 20, 30 mg/kg; single dose; first day and 2, 4 and 6 week after infection
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Result:Reduced Colony Forming Units (CFU) counts of Mycobacteria in spleen of beige mice.
Chemical Information
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CAS No. 103051-26-9
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Molecular Weight 459.37
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Formula C26H20Cl2N4
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SMILES
CC/N=C1C=C2N(C3=C(N=C2C=C\1NC4=CC=C(C=C4)Cl)C=CC=C3)C5=CC=C(C=C5)Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)