![[MePhe7]-Neurokinin B](https://file.medchemexpress.com/product_pic/hy-p3862.gif "Click to View [MePhe7]-Neurokinin B Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Neurokinin B
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Neurokinin B" in MCE Product Catalog:
Cat. No.: HY-P0242
CAS No.: 86933-75-7
3
3 Cited Publications
Cat. No.: HY-P75951
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; Transmembrane Glycoprotein HGFIN; Glycoprotein (Transmembrane) Nmb; Uncharacterized Protein GPNMB; Transm
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P77116
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; Transmembrane Glycoprotein HGFIN; Glycoprotein (Transmembrane) Nmb; Uncharacterized Protein GPNMB; Transm
Species:
Mouse
Source:
HEK293
Synonyms: NT-814; BAY3427080
Target:
Research Areas:
Elinzanetant is an orally active and selective NK-1 and NK-3 receptor antagonist. Elinzanetant alleviates menopause-associated vasomotor symptoms, including hot flashes and night sweats. Elinzanetant reduces estradiol and progesterone levels. Elinzanetant can be used for the research of moderate to severe vasomotor and sleep disorders associated with menopause .
Cat. No.: HY-P0242A
CAS No.: 101536-55-4
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
Synonyms: GW679769B
Target:
Research Areas:
Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) .
Cat. No.: HY-P3862
CAS No.: 110880-53-0
Target:
Research Areas:
Cat. No.: HY-P3847
CAS No.: 131019-53-9
Synonyms: Tyr-NKB
Target:
Research Areas:
Cat. No.: HY-P3850
CAS No.: 109212-72-8
Target:
Research Areas:
Cat. No.: HY-138106
CAS No.: 200344-33-8
Target:
Research Areas:
Cat. No.: HY-116822
CAS No.: 264618-44-2
Target:
Research Areas:
SSR 146977 is a potent and selective antagonist of the tachykinin NK3 receptor. SSR 146977 inhibits the binding of radioactive neurokinin B to NK3 receptors in Chinese hamster ovary cells, with a Ki of 0.26 nM .
Cat. No.: HY-19633A
CAS No.: 216776-73-7
Target:
Research Areas:
CS-003 is a triple neurokinin receptor antagonist with activity in inhibiting neurokinin-related respiratory diseases. CS-003 exhibits high affinity for human neurokinin 1, 2 and 3 receptors, withKi values of 2.3 nM, 0.54 nM and 0.74 nM respectively. The Ki values of CS-003 on the guinea pig neurokinin receptor are 5.2 nM, 0.47 nM and 0.71 nM respectively, showing superior inhibitory effect. CS-003 significantly inhibits the formation of inositol phosphate involving substance P, neurokinin A and neurokinin B through competitive antagonism. CS-003 significantly inhibits citric acid-induced cough, and its effect is better than other selective neurokinin receptor antagonists .
Cat. No.: HY-116620
CAS No.: 157047-98-8
Target:
Cat. No.: HY-B1392R
CAS No.: 81161-17-3
Research Areas:
Esmolol hydrochloride (Standard) is the analytical standard of Esmolol hydrochloride (HY-B1392).This product is intended for research and analytical applications. Esmolol hydrochloride is an ultra-short-acting cardioselective β1-adrenergic blocker. Esmolol hydrochloride exerts its antiarrhythmic effect by activating Neurokinin 1 Receptorb. Esmolol hydrochloride attenuates post resuscitation myocardial dysfunction. Esmolol hydrochloride improves diabetic wound healing by inhibiting aldose reductase and the production of advanced glycation end products and promoting fibroblast migration. Esmolol hydrochloride can be used to study cardiac diseases such as arrhythmias and diabetic foot ulcers .
Cat. No.: HY-B1392S
CAS No.: 1346598-13-7
Cat. No.: HY-116268
CAS No.: 1133706-08-7
Target:
Research Areas:
GSK256471 is a non-peptide tachykinin NK3 receptor antagonist with a pKi of 8.9 for the human recombinant NK3 receptor and 8.4 for the guinea pig native receptor. GSK256471 exhibits >100-fold selectivity for NK1 (pKi = 5.2) and NK2 (pKi = 7.3) receptors. GSK256471 noncompetitively inhibits neurokinin B (NKB) (HY-P0242)-induced inositol phosphate accumulation, and this inhibition is irreversible. GSK256471 inhibits wet dog shaking behavior and suppresses dopamine release. GSK256471 could be used to study schizophrenia .
Cat. No.: HY-P71349
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TAC3; Tachykinin-3; Prev. NKNB; Neurokinin-B Protein; ZNEUROK1; Preprotachykinin-B; LncZBTB39-1:2; Gamma Tachykinin 3; LncZBTB39; Preprotachykinin B; NKB; Neurokinin Beta; NK3; PRO1155; Neuromedin K; HH10; Tachykinin 3; Tachykinin Precursor 3; Neurokinin
Species:
Human
Source:
E. coli
Cat. No.: HY-P70836
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; Transmembrane Glycoprotein HGFIN; Glycoprotein (Transmembrane) Nmb; Uncharacterized Protein GPNMB; Transm
Species:
Human
Source:
HEK293
Cat. No.: HY-P75950
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; Transmembrane Glycoprotein HGFIN; Glycoprotein (Transmembrane) Nmb; Uncharacterized Protein GPNMB; Transm
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
