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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
PROTAC BRAF-V600E degrader-2
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "PROTAC BRAF-V600E degrader-2" in MCE Product Catalog:
Cat. No.: HY-137488
CAS No.: 2417296-82-1
PROTAC BRAF-V600E degrader-2 is a PROTAC degrader targeting BRAF-V600E. The Kd values of PROTAC BRAF-V600E degrader-2 for BRAF and BRAF-V600E are 14.4 nM and 9 nM, respectively. PROTAC BRAF-V600E degrader-2 selectively degrades BRAF-V600E but does not degrade wild-type BRAF. PROTAC BRAF-V600E degrader-2 inhibits the MEK/ERK kinase cascade and suppresses the growth of melanoma cells. PROTAC BRAF-V600E degrader-2 can be used in studies related to melanoma and colon cancer .
Cat. No.: HY-W074340
CAS No.: 63984-03-2
Target:
Research Areas:
tert-Butyl 5-aminopentanoate is a PROTAC linker. tert-Butyl 5-aminopentanoate can be used to synthesize the PROTAC BRAF-V600E degrader-2 (HY-137488).
Cat. No.: HY-184546
CAS No.: 2417296-80-9
Research Areas:
BRAFV600E ligand-1 is a BRAFV600E ligand. BRAFV600E ligand-1 can serve as a target protein ligand for the synthesis of BRAFV600E PROTAC degraders, such as PROTAC BRAF-V600E degrader-2 (HY-137488) .
Cat. No.: HY-184581
CAS No.: 2412056-33-6
Research Areas:
Pomalidomide-5-C4-acid is an E3 ligase ligand-linker conjugate that can be used for PROTAC synthesis, such as PROTAC BRAF-V600E degrader-2 (HY-137488) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
