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Results for "

Pancreas

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (2) Amylases (2) Antibody-Drug Conjugates (ADCs) (1) AP-1 (1) Apoptosis (3) Bacterial (1) Biochemical Assay Reagents (9) Bombesin Receptor (1) Caspase (1) CD3 (1) Chloride Channel (2) Cholecystokinin Receptor (5) COX (1) DNA/RNA Synthesis (9) Drug Derivative (1) E-Selectin (1) EGFR (1) Elastase (2) Endogenous Metabolite (10) Endonuclease (4) Ferroptosis (1) FLT3 (1) Free Fatty Acid Receptor (1) Fungal (1) GABA Receptor (4) GCGR (1) GLP Receptor (1) Guanylate Cyclase (1) IFNAR (1) IKK (1) Insulin Receptor (2) Interleukin Related (3) Isotope-Labeled Compounds (4) JNK (1) Liposome (1) mRNA (4) NADPH Oxidase (1) Neuropeptide Y Receptor (4) NF-κB (2) NO Synthase (1) P2Y Receptor (1) PI3K (3) Potassium Channel (4) Proteasome (1) Ras (1) Reactive Oxygen Species (ROS) (1) Reference Standards (5) Secretin Receptor (3) Ser/Thr Protease (4) Sodium Channel (2) TGF-β Receptor (1) TNF Receptor (1)
By Research Areas:	Cancer (26) Cardiovascular Disease (5) Endocrinology (12) Infection (3) Inflammation/Immunology (15) Metabolic Disease (29) Neurological Disease (11)
Oligonucleotides:	Transcription Factors (3) mRNA (4)

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Isotope-Labeled Compounds

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Oligonucleotides

Cat. No.	상품명	Target	연구분야	Chemical Structure

HY-108882

DNase I, Bovine pancreas Maximum Cited Publications 29 Publications Verification DNase	Others	Inflammation/Immunology Cancer
DNase I (EC 3.1.21.1) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer .

HY-P2974

Elastase, Porcine pancreas 4 Publications Verification EC 3.4.21.36; Pancreatopeptidase E	Elastase	Metabolic Disease
Elastase, Porcine pancreas (EC 3.4.21.36) is a single polypeptide chain of 240 amino acid residues, derived from pig pancreas. Elastase, Porcine pancreas is a serine protease that can hydrolyze proteins and polypeptide. Elastase from porcine pancreas can induce emphysema in hamsters .

HY-129046

RNase A, Bovine pancreas 5 Publications Verification Ribonuclease A; EC 4.6.1.18; RNase A	Endonuclease DNA/RNA Synthesis	Others
RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability .

HY-P0093

Sincalide 4 Publications Verification Cholecystokinin octapeptide; CCK-8; SQ19844	Cholecystokinin Receptor Apoptosis PI3K Akt	Infection Cancer
Sincalide (Cholecystokinin octapeptide, CCK-8) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK. Sincalide can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide is a major bioactive segment of CCK that retains most of the biological activities of CCK .

HY-B2118

Pancreatin 5+ Cited Publications	Biochemical Assay Reagents	Metabolic Disease
Pancreatin is the porcine pancreas extract (PPE) which contains the main pancreatic digestive enzymes .

HY-129047E

*Trypsin, porcine pancreas* (Cell culture grade)** 15+ Cited Publications	Ser/Thr Protease	Others
Trypsin, porcine pancreas (Cell culture grade) is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine residues. Trypsin, porcine pancreas (Cell culture grade) exhibits excellent protein digestibility for α-lactalbumin and β-casein. Trypsin, porcine pancreas (Cell culture grade) removes cellular components while preserving extracellular matrix structures to achieve uniform decellularization of porcine pancreas .

HY-W017227

Alloxan hydrate 1 Publications Verification	Proteasome	Metabolic Disease Cancer
Alloxan hydrate is a diabetogenic agent to induce diabetes. Alloxan hydrate is a proteasome inhibitor. Alloxan causes diabetes in experimental animals through its ability to destroy the insulin-secreting B-cells of the pancreas .

HY-12461

WS6	PI3K EGFR GABA Receptor FLT3 IKK	Neurological Disease Metabolic Disease Inflammation/Immunology
WS6 is an IkB kinase and EBP1 inhibitor, with IC₅₀ values of 0.24 nM, 0.21 nM, and 40.48 nM in MV4-11, MOLM13, and K562 cells, respectively. WS6 promotes the proliferation of alpha and beta cells in the pancreas, has antioxidant and anti-inflammatory activities, and can alleviate depression like behavior in rats ^[1][2][4].

HY-129046C

RNase B, Bovine Pancreas Ribonuclease B, Bovine Pancreas	Endonuclease DNA/RNA Synthesis	Endocrinology Cancer
RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase B, Bovine Pancreas (Ribonuclease B, Bovine Pancreas) is the N-glycosylated form of RNase A. RNase B, Bovine Pancreas can promote the folding of polypeptide chains and play a role similar to molecular chaperones .

HY-W116336D

Zinc oxide, <100 nm particle size	Biochemical Assay Reagents Fungal Bacterial	Infection Cancer
Zinc oxide, <100 nm particle size is a nitrate reductase modulator and growth promoter with plant stress resistance activity and oral toxicity. Zinc oxide, <100 nm particle size acts as a nutrient source for maize plants. By enhancing nitrate reductase activity and reducing free proline levels, it significantly improves plant height, root length and dry matter weight of maize, and its growth-promoting effect is comparable to that of traditional zinc sulfate fertilizer. Zinc oxide, <100 nm particle size induces anemia-related and persistent tissue inflammatory damage, leading to obvious histopathological adverse reactions in the stomach, pancreas, eyes and prostate of rats. Zinc oxide, <100 nm particle size acts as a non-toxic antibacterial agent and selective cytotoxin against multiple bacteria, fungi and spores .

HY-P2746

Carboxypeptidase B, Porcine pancreas EC 3.4.2.2	Endogenous Metabolite	Metabolic Disease
Carboxypeptidase B, Porcine pancreas (EC 3.4.2.2) is a peptide exonuclease that can specifically degrade peptide chains. Carboxypeptidase B is progressively degraded from the C-terminal to release free amino acids. Carboxypeptidase B hydrolyzes only peptide bonds with basic amino acids (such as arginine and lysine) as C-terminal residues .

HY-B2192

Amylase	Amylases	Metabolic Disease Cancer
Amylase is an enzyme produced by pancreas and salivary glands, catalyzing the hydrolysis of starch into sugars. Amylase are broadly classified into α, β, and γ subtypes .

HY-108882C

DNase I (filtered)	DNA/RNA Synthesis	Inflammation/Immunology
DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune reactions. Decreased DNase I activity may be associated with the occurrence and development of systemic lupus erythematosus (SLE). DNase I (filtered) is filtered through a 0.22 μM membrane and is not tested for pyrogenicity .

HY-108882B

DNase I RNase & Protease free Maximum Cited Publications 29 Publications Verification	DNA/RNA Synthesis	Inflammation/Immunology
DNase I is an enzyme that degrades DNA. DNase I is mainly produced by digestive system organs, such as the pancreas and parotid gland. Three types of DNase I are known in mammals: pancreatic type, parotid type, and pancreatico-parotid type. DNase I plays a key role in the cleavage of extracellular DNA, and is critical for limiting inflammatory responses and maintaining homeostasis. DNase I is responsible for digesting extracellular nucleoproteins, which may be essential for preventing autoimmune responses. Decreased DNase I activity may be associated with the onset and progression of systemic lupus erythematosus (SLE). DNase I (RNase & Protease free) is a molecular biology-grade DNase I purified by chromatography to remove RNase and protease .

HY-P99152

Muromonab Muromanab-CD3	CD3 Interleukin Related IFNAR	Inflammation/Immunology Cancer
Muromonab (Muromonab-CD3; OKT3) is a mouse monoclonal antibody targeting the CD3 antigen. Muromonab specifically binds to the CD3 antigen on the surface of human and higher primate T cells. Muromonab blocks the function of T cell receptors to recognize foreign antigens and inhibits T cell-mediated immune responses, including cell-mediated lymphocyte lysis and T cell proliferation responses. Muromonab can be used to study acute kidney, liver, heart and combined kidney-pancreas transplant rejection, and can also be used to study graft-versus-host disease in bone marrow transplant patients .

HY-134353B

ADP-β-S trilithium Adenosine 5'-β-thiodiphosphate trilithium	P2Y Receptor NF-κB Interleukin Related Caspase	Neurological Disease Inflammation/Immunology Cancer
ADP-β-S (Adenosine 5'-(β-thiodiphosphate)) trilithium is a non-hydrolyzable ADP analog and a P2Y12 receptor agonist. ADP-β-S trilithium activates the P2Y12 receptor in microglia, thereby triggering downstream inflammatory signaling pathways. ADP-β-S trilithium activates P2Y purinergic receptors in rat pancreatic β cells and enhances glucose-induced insulin secretion. ADP-β-S trilithium can be used in the research of diseases such as inflammation and diabetes .

HY-B0881

Acetohexamide 2 Publications Verification	Potassium Channel	Metabolic Disease Cancer
Acetohexamide is an orally active first-generation sulfonylurea agent used in research related to type 2 diabetes and cancer. Acetohexamide exerts reductase activity in human erythrocytes. Acetohexamide stimulates the pancreas to secrete insulin. Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas. Acetohexamide can inhibit the formation of circular chemorepellent induced defects (CCIDs) in lymphendothelial cell (LEC) monolayers. Acetohexamide inhibits markers of epithelial-to-mesenchymal-transition and migration. Acetohexamide suppresses the synthesis of 12(S)-HETE. Acetohexamide can potentiate hypoglycaemic action .

HY-P1096

A71623	Cholecystokinin Receptor	Metabolic Disease
A71623, a CCK-4-based peptide, is a potent and highly selective CCK-A full agonist. The IC₅₀s for A-71623 are 3.7 nM in guinea pig pancreas (CCK-A) and 4500 nM in cerebral cortex (CCK-B) in radioligand binding assays, respectively .

HY-112052

Aminomalonic acid 1 Publications Verification	Endogenous Metabolite	Cancer
Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (K_i= 0.0023 M) and mouse pancreas (K_i= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis .

HY-19694

BRD7552	Insulin Receptor	Endocrinology
BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function .

HY-P0093A

Sincalide ammonium 4 Publications Verification Cholecystokinin octapeptide ammonium; CCK-8 ammonium; SQ19844 ammonium	Cholecystokinin Receptor Apoptosis PI3K Akt	Infection Cancer
Sincalide ammonium (Cholecystokinin octapeptide ammonium, CCK-8 ammonium) is a rapid-acting amino acid polypeptide hormone analogue of cholecystokinin (CCK) for intravenous use in postevacuation cholecystography. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK. CCK‐8 can promote gallbladder contraction by injection and helps diagnose gallbladder and pancreas disorders. Sincalide ammonium can increase bile secretion, cause the gallbladder to contract and relax the sphincter of Oddi, resulting in bile drainage into the duodenum. Sincalide ammonium is a major bioactive segment of CCK that retains most of the biological activities of CCK .

HY-P2879A

Cholesterol esterase, Porcine pancreas	Biochemical Assay Reagents	Metabolic Disease
Cholesterol esterase, Porcine pancreas is an enzyme that hydrolyzes cholesteryl esters into cholesterol and free fatty acids in the intestine. Cholesterol esterase, also known as bile salt-stimulated lipase or carboxyl ester lipase, functions to promote cholesterol absorption .

HY-P2980

Carboxypeptidase A, Bovine pancreas EC 3.4.2.1	Endogenous Metabolite	Others
Carboxypeptidase A, Bovine pancreas (EC 3.4.2.1) is a zinc-containing metalloprotease, is often used in biochemical studies. Carboxypeptidase A catalyzes the hydrolysis of the peptide bonds that are adjacent to the C-terminal end of a polypeptide chain. Carboxypeptidase A is a prototypical enzyme for metalloproteases that plays important roles in biological systems .

HY-P2942

Chymotrypsinogen	Ser/Thr Protease	Inflammation/Immunology
Chymotrypsinogen is an inactive precursor of Chymotrypsin (HY-108910). Chymotrypsin is a serine protease produced by the pancreas .

HY-107482

Picamilon Nicotinoyl-GABA; Nicotinoyl-γ-aminobutyric acid	GABA Receptor	Neurological Disease
Picamilon is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .

HY-162809

XMU-MP-9	Ras	Cancer
XMU-MP-9 is a bifunctional compound that binds to the C2 domain of Nedd4-1 and the allosteric site of K-Ras. XMU-MP-9 enhances the interaction between Nedd4-1 and K-Ras, induces conformational changes in the Nedd4-1/K-Ras complex, promotes the ubiquitination and degradation of multiple K-Ras mutants, and inhibits the proliferation of cells carrying K-Ras mutants. XMU-MP-9 can be used for the study of colon, lung and pancreatic cancer .

HY-P2795

Kallikrein, Porcine pancreas kininogenase; SK-827	Endogenous Metabolite	Others
Kallikrein, Porcine pancreas (kininogenase) is capable of forming the kallikrenase kalinin system (KKS) in plasma and tissues, producing bradykinin and kalin peptides, respectively .

HY-B2193B

α-Amylase, Human Pancreas Amylase, a-Amylase, 1,4-a-D-glucan glucanohydrolase, glycogenase	Biochemical Assay Reagents	Others
α-Amylase, Human Pancreas (Amylase) is a hydrolase enzyme that can be isolated from human pancreas. α-Amylase, Human Pancreas catalyses the hydrolysis of internal α-1, 4-glycosidic linkages in starch to yield products like glucose and maltose. α-Amylase, Human Pancreas can be used in life science research .

HY-W011240

Hydroflumethiazide Methforylthiazidine; Rontyl	Sodium Channel Chloride Channel	Metabolic Disease Endocrinology
Hydroflumethiazide (Methforylthiazidine) is an orally active and potent thiazide diuretic. Hydroflumethiazide possesses the ability to directly stimulate A cell secretion in the normal and alloxan diabetic pancreas .

HY-P4060

Pancreatic polypeptide	Neuropeptide Y Receptor	Metabolic Disease Endocrinology
Pancreatic polypeptide is a peptide secreted by the endocrine PP cells of the pancreas that regulates pancreatic secretory activity and also affects hepatic glycogen stores and gastrointestinal secretion .

HY-124424

VU0071063	Potassium Channel	Others Neurological Disease
VU0071063 is a potent and specific Kir6.2/SUR1 opener (EC₅₀=7.44 μM) and can be used for investigating Kir6.2/SUR1 expressed in the pancreas and brain. VU0071063 inhibits insulin secretion by inducing hyperpolarization of β-cell membrane potential. VU0071063 chemotype has a very steep structure-activity relationships .

HY-172404

Arylsulfatase	Endogenous Metabolite	Cancer
Arylsulfatase is a hydrolase with substrate specificity for potassium 6-benzoyl-2-naphthyl sulfate. Arylsulfatase exhibits optimal activity at 37°C, and its incubation time is tissue-dependent. Arylsulfatase can be used in tumor-related research .

HY-P3863

Pancreastatin (swine)	Ser/Thr Protease	Inflammation/Immunology
Pancreastatin (swine) is a 49-residue peptide which strongly inhibits glucose-induced insulin release. Pancreastatin (swine) can be isolated and characterized from porcine pancreas .

HY-129046B

*RNase A, Bovine Pancreas* DNase & Protease Free** Ribonuclease A DNase & Protease Free	Endonuclease DNA/RNA Synthesis	Others Endocrinology Cancer
RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A, Bovine Pancreas (DNase & Protease Free) is RNase A derived from bovine pancreas and does not contain DNase or protease .

HY-129046E

RNase A DNase & Protease Free, Recombinant Ribonuclease A DNase & Protease Free, Recombinant	Endonuclease DNA/RNA Synthesis	Endocrinology Cancer
RNase A (Bovine pancreatic RNase) is a widely used Endonuclease in DNA purification by specifically hydrolyzing cytosine or uracil residues of RNA. RNase A degrades the RNA in the RNA/DNA duplex. RNase A catalyses the breakdown of 3',5'-phosphodiester linkages of single stranded RNA. RNase A family members in organisms are tightly involved in various physiological and pathological processes including cell growth and development, proliferation, differentiation and migration. Dysregulation of RNase A activity or expression level is closely related to pancreatic, ovarian, bladder and thyroid cancer. RNase A has tumor cell-killing ability. RNase A (DNase & Protease Free), Recombinant is recombinant RNase A, which does not contain DNase and protease .

HY-P1244A

Secretin (33-59), rat TFA Secretin (rat) TFA	Secretin Receptor	Neurological Disease
Secretin (33-59), rat (TFA) is a 27-aa peptide, which acts on secretin receptor, and enhances the secretion of bicarbonate, enzymes, and K ⁺ from the pancreas .

HY-P0039

BIM-26226	Bombesin Receptor	Cancer
BIM-26226 is a selective gastrin-releasing peptide receptor (GRPR) (IC₅₀ = 6 nM) and bombesin receptor (BN receptor) antagonist. BIM-26226 antagonizes BN- or GRP-stimulated amylase release with IC₅₀ values of 0.3 nM and 0.2 nM, respectively. BIM-26226 is specific for the GRP-preferring BN receptor subtype with no interference with GRP receptor system. BIM-26226 can induce the synthesis of somatostatin receptor but has no significant effect on tumor growth .

HY-P99662

Indusatumab vedotin MLN0264; TAK-264	Antibody-Drug Conjugates (ADCs) Guanylate Cyclase Apoptosis	Cancer
Indusatumab vedotin (MLN-0264; AKT-264) is an antibody-drug conjugate (ADC) consisting of the human anti-guanylate cyclase C (GCC) antibody linked to a microtubule-disruptor Monomethyl auristatin (HY-15162). Indusatumab vedotin has anti-proliferative effects on pancreas cancer cell lines. Indusatumab vedotin arrests cell cycle at G2/M phase, and induces apoptosis .

HY-P1025A

M40 TFA	Neuropeptide Y Receptor	Cardiovascular Disease Neurological Disease
M40 TFA is the TFA salt form of M40. M40 TFA is an antagonist or a weak agonist for galanin receptor depending on different subtypes of galanin receptors in the brain, hypothalamus, hippocampus, amygdala and pancreas .

HY-W854385A

Sialyl Lewis A sodium 1 Publications Verification SLeA sodium	Biochemical Assay Reagents	Cancer
Sialyl Lewis A (SLeA) sodium is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A sodium promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A sodium shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A sodium can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .

HY-W854385

Sialyl Lewis A SLeA	Biochemical Assay Reagents E-Selectin	Cancer
Sialyl Lewis A (SLeA) is a tumor-associated carbohydrate antigen, also known as carbohydrate antigen 19-9 (CA19-9), that binds to E-selectin (ELAM-1) and selectins to mediate cell-endothelium adhesion. Sialyl Lewis A promotes cancer cell-vascular endothelium adhesion, and its surface presence correlates with increased tumorigenicity and invasiveness in cancer cells. Sialyl Lewis A shows elevated expression in human adenocarcinomas of the colon, pancreas, and stomach, with expression levels linked to tumor progression and poor prognosis in colorectal and gastric carcinomas. Sialyl Lewis A can be used for the research of cancers, such as colon, pancreas, stomach, and squamous lung cancer .

HY-107482A

Picamilon sodium Nicotinoyl-GABA sodium; Nicotinoyl-γ-aminobutyric acid sodium; Sodium 4-(nicotinamido)butanoate	GABA Receptor	Neurological Disease
Picamilon sodium is an orally active derivative of γ-aminobutyric acid that has nootropic effect. Picamilon sodium improves the epilepsy model in rats and promotes correction of functional disorders of the pancreas during Alloxan (HY-W017227)-induced diabetes mellitus in rats .

HY-176838

LXT34	Free Fatty Acid Receptor GLP Receptor	Inflammation/Immunology
LXT34 (Example 2) is a GPR120 agonist. LXT34 has an anti-inflammatory activity. LXT34 promotes GLP-1 formation in the gastrointestinal tract and improves insulin resistance in macrophages and pancreas cells. LXT34 can be used for inflammatory diseases, such as type 2 diabetes, obesity and non-alcoholic fatty liver research .

HY-107372S2

Uridine triphosphate-13C9 dilithium UTP-13C9 dilithium; Uridine 5'-triphosphate-13C9 dilithium	Isotope-Labeled Compounds Endogenous Metabolite DNA/RNA Synthesis	Cardiovascular Disease Inflammation/Immunology Cancer
Uridine triphosphate- ¹³C₉ (UTP- ¹³C₉ dilithium; Uridine 5'-triphosphate- ¹³C₉) dilithium is ¹³C-labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-178363

α-Amylase-IN-13	Amylases	Metabolic Disease Endocrinology
α-Amylase-IN-13 is an orally active, selective, brain-penetrant α-amylase inhibitor (IC₅₀ = 0.71 μM). α-Amylase-IN-13 inhibits α-amylase through a mixed type of inhibition mechanism. α-Amylase-IN-13 leads to a significant reduction in blood glucose level in diabetic rats. α-Amylase-IN-13 causes significant histopathological improvements in the kidney, liver, and pancreas. α-Amylase-IN-13 can be used for the study of diabetic complications .

HY-P1244

Secretin (33-59), rat Secretin (rat)	Secretin Receptor	Neurological Disease
Secretin (33-59), rat is a 27-aa peptide, acts on secretin receptor, enhances the secretion of bicarbonate, enzymes, and K ⁺ from the pancreas.

HY-P1025

M40	Neuropeptide Y Receptor	Cardiovascular Disease Neurological Disease
M40 is an antagonist or a weak agonist for galanin receptor depending on different subtypes of galanin receptors in the brain, hypothalamus, hippocampus, amygdala and pancreas .

HY-P3621

Biotinyl-Glucagon (1-29), human, bovine, porcine	GCGR	Metabolic Disease
Biotinyl-Glucagon (1-29), human, bovine, porcine is a biotinylated glucagon. Glucagon is a peptide hormone, produced by α-cells of the pancreas, can increase concentration of glucose and fatty acids in the bloodstream .

HY-P1537

Pancreatic Polypeptide, bovine	Neuropeptide Y Receptor	Metabolic Disease Endocrinology
Pancreatic Polypeptide, bovine, a 36-amino acid, straight chain polypeptide derived primarily from the pancreas, inhibits secretin- and cholecystokinin-stimulated pancreatic secretion; Pancreatic Polypeptide, bovine acts as an agonist of NPY receptor, with high affinity at NPYR4.

HY-174557

Human PAX6 mRNA	mRNA	Metabolic Disease
Human PAX6 mRNA encodes the human paired box 6 (PAX6) protein, a member of the paired box (PAX) family. PAX6 may play an important role in the development of the eye, nose, central nervous system and pancreas. It is also required for the differentiation of pancreatic islet alpha cells.

Cat. No.	상품명	Category	Target	Chemical Structure

HY-B2192

Amylase	Natural Products Microorganisms other families Animals Classification of Application Fields Metabolic Disease Plants Disease Research Fields Source Classification	Amylases
Amylase is an enzyme produced by pancreas and salivary glands, catalyzing the hydrolysis of starch into sugars. Amylase are broadly classified into α, β, and γ subtypes .

HY-112052

Aminomalonic acid 1 Publications Verification	Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (K_i= 0.0023 M) and mouse pancreas (K_i= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis .

HY-N16527

7-O-Galloyl-D-sedoheptulose	Structural Classification Cornaceae Cornus officinalis Sieb. et Zucc. Phenols Polyphenols Plants Source Classification	TNF Receptor Interleukin Related NADPH Oxidase Reactive Oxygen Species (ROS) NF-κB COX NO Synthase JNK AP-1 TGF-β Receptor
7-O-Galloyl-D-sedoheptulose is an orally effective polyphenolic compound. 7-O-Galloyl-D-sedoheptulose lowers the serum levels of glucose, leptin, insulin, C-peptide, resistin, TNF-α, IL-6, and increases the serum level of adiponectin. 7-O-Galloyl-D-sedoheptulose significantly reduces the levels of ROS and lipid peroxidation products (TBARS) by down-regulating the protein expression of NADPH oxidase subunit Nox-4 and p22phox. 7-O-Galloyl-D-sedoheptulose down-regulates NF-κB and related pro-inflammatory factors (COX-2, iNOS), inhibits the phosphorylation of JNK and the activity of its downstream AP-1. 7-O-Galloyl-D-sedoheptulose reduces the expression of TGF-β1 and fibronectin, indicating its potential in anti-tissue fibrosis. 7-O-Galloyl-D-sedoheptulose can be used for the study of type 2 diabetes and its hepatic and pancreatic complications .

HY-112052R

Aminomalonic acid (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Aminomalonic acid (Standard) is the analytical standard of Aminomalonic acid (HY-112052). This product is intended for research and analytical applications. Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (K_i= 0.0023 M) and mouse pancreas (K_i= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis .

HY-W014610

Strawberry aldehyde Ethyl methylphenylglycidate	Structural Classification Natural Products Rosaceae Plants Fragaria × ananassa Duch. Source Classification	Biochemical Assay Reagents
Strawberry aldehyde is an orally active synthetic flavor compound widely used in the food and cosmetics industries. Its presence in small cigar smoke shows a significant positive correlation with free radical levels, thereby increasing the toxicity of the smoke. Strawberry aldehyde has demonstrated long-term safety in rats .

Cat. No.	상품명	Chemical Structure

HY-107372S2

Uridine triphosphate-13C9 dilithium

Uridine triphosphate- ¹³C₉ (UTP- ¹³C₉ dilithium; Uridine 5'-triphosphate- ¹³C₉) dilithium is ¹³C-labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-W703629

Acetohexamide-d11
Acetohexamide-d₁₁ is the deuterium labeled Acetohexamide (HY-B0881). Acetohexamide is a first-generation sulfonylurea agent used in research related to type 2 diabetes; it stimulates the pancreas to secrete insulin.Acetohexamide inhibits ATP-sensitive potassium channels in the β cells of the pancreas .

HY-107372S4

Uridine triphosphate-15N2 dilithium

Uridine triphosphate- ¹⁵N₂ (UTP- ¹⁵N₂ dilithium; Uridine 5'-triphosphate- ¹⁵N₂) dilithium is ¹⁵N labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

HY-107372S3

Uridine triphosphate-d13 dilithium

Uridine triphosphate-d₁₃ (UTP-d₁₃ dilithium; Uridine 5'-triphosphate-d₁₃) dilithium is deuterium labeled Uridine triphosphate (HY-107372). Uridine triphosphate (UTP;Uridine 5'-triphosphate) is a nucleotide that regulates the functions of the pancreas in endocrine and exocrine secretion, proliferation, channels, transporters, and intracellular signaling under normal and disease states.

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