1068-84-4
1068-84-4
Chemical Structure
Aminomalonic acid
- CAS No.: 1068-84-4
- Formula:C3H5NO4
- Molecular Weight:119.08
IUPAC Name: 2-aminomalonic acid
InChIKey: JINBYESILADKFW-UHFFFAOYSA-N
SMILES: O=C(O)C(N)C(O)=O
Biological Activity: Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Aminomalonic acid | 99.97% | Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis. | ||||||||||||||||||||
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Aminomalonic acid (Standard) | ≥98% | Aminomalonic acid (Standard) is the analytical standard of Aminomalonic acid (HY-112052). This product is intended for research and analytical applications. Aminomalonic acid is an amino endogenous metabolite, acts as a strong inhibitor of L-asparagine synthetase from Leukemia 5178Y/AR (Ki= 0.0023 M) and mouse pancreas (Ki= 0.0015 M) in vitro. Aminomalonic acid is a potential biomarker to discriminate between different stages of melanoma metastasis. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.85
HY-42068(-)-Aspartic acid -
Similarity Score 0.85
HY-N0666RL-Aspartic acid (Standard) -
Similarity Score 0.85
HY-N0666S1L-Aspartic acid-13C4,15N -
Similarity Score 0.85
HY-N0666S3L-Aspartic acid-15N -
Similarity Score 0.85
HY-N0666S4L-Aspartic acid-13C4 -
Similarity Score 0.85
HY-N0666S6L-Aspartic acid-1,4-13C2 -
Similarity Score 0.85
HY-N0666S7L-Aspartic acid-1,4-13C2,15N -
Similarity Score 0.85
HY-W015824RDL-Aspartic acid (Standard) -
Similarity Score 0.85
HY-W015824SDL-Aspartic acid-13C -
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References
- [1]. Van Buskirk JJ, et al. Aminomalonic acid: identification in Escherichia coli and atherosclerotic plaque. Proc Natl Acad Sci U S A. 1984 Feb;81(3):722-5. [Content Brief]
- [2]. Milman HA, et al. Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase. Enzyme. 1979;24(1):36-47. [Content Brief]
- [3]. Kim HY, et al. Discovery of potential biomarkers in human melanoma cells with different metastatic potential by metabolic and lipidomic profiling. Sci Rep. 2017 Aug 18;7(1):8864. [Content Brief]
