L-Aspartic acid-15N
Based on 1 Customer Validation
L-Aspartic acid-15N is the 15N-labeled L-Aspartic acid. L-Aspartic aicd is an amino acid that can penetrate the blood-brain barrier. L-Aspartic aicd is commonly used for preparing prodrugs to target colon and cecal tissues. L-Aspartic aicd commonly used in the study of inflammatory conditions.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 3715-16-0
- Formula: C4H715NO4
- Molecular Weight:134.10
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 3715-16-0
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Unlabeled Cas 56-84-8
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Appearance Solid
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Molecular Weight 134.10
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Formula C4H715NO4
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Color White to off-white
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SMILES
OC(C[C@H]([15NH2])C(O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
1 M NaOH : 100 mg/mL (745.71 mM; ultrasonic and adjust pH to 12 with NaOH)
H2O : 2 mg/mL (14.91 mM; ultrasonic and warming and heat to 60°C)
DMSO : 1 mg/mL (7.46 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Leopold CS, et al. In vivo pharmacokinetic study for the assessment of poly(L-aspartic acid) as a drug carrier for colon-specific drug delivery. J Pharmacokinet Biopharm. 1995 Aug;23(4):397-406. [Content Brief]
[2]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. J Neurochem. 1999 Sep;73(3):1206-11. [Content Brief]
[3]. Su G, et al. Enteric coronavirus PDCoV evokes a non-Warburg effect by hijacking pyruvic acid as a metabolic hub. Redox Biol. 2024 May;71:103112. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O / 1 M NaOH | 1 mM | 7.4571 mL | 37.2856 mL | 74.5712 mL | 186.4280 mL |
| 5 mM | 1.4914 mL | 7.4571 mL | 14.9142 mL | 37.2856 mL | |
| H2O / 1 M NaOH | 10 mM | 0.7457 mL | 3.7286 mL | 7.4571 mL | 18.6428 mL |
| 1 M NaOH | 15 mM | 0.4971 mL | 2.4857 mL | 4.9714 mL | 12.4285 mL |
| 20 mM | 0.3729 mL | 1.8643 mL | 3.7286 mL | 9.3214 mL | |
| 25 mM | 0.2983 mL | 1.4914 mL | 2.9828 mL | 7.4571 mL | |
| 30 mM | 0.2486 mL | 1.2429 mL | 2.4857 mL | 6.2143 mL | |
| 40 mM | 0.1864 mL | 0.9321 mL | 1.8643 mL | 4.6607 mL | |
| 50 mM | 0.1491 mL | 0.7457 mL | 1.4914 mL | 3.7286 mL | |
| 60 mM | 0.1243 mL | 0.6214 mL | 1.2429 mL | 3.1071 mL | |
| 80 mM | 0.0932 mL | 0.4661 mL | 0.9321 mL | 2.3304 mL | |
| 100 mM | 0.0746 mL | 0.3729 mL | 0.7457 mL | 1.8643 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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