L-Aspartic acid-1,4-13C2
Based on 1 Customer Validation
L-Aspartic acid-1,4-13C2 is the 13C-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy.
For research use only. We do not sell to patients.
- CAS No.: 101247-29-4
- Formula: C213C2H7NO4
- Molecular Weight:135.09
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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NMDA Receptor |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 101247-29-4
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Unlabeled Cas 56-84-8
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Appearance Solid
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Molecular Weight 135.09
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Formula C213C2H7NO4
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Color White to off-white
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SMILES
O[13C](C[C@H](N)[13C](O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
1 M NaOH : 100 mg/mL (740.25 mM; ultrasonic and adjust pH to 12 with NaOH)
H2O : 2 mg/mL (14.80 mM; ultrasonic and warming and heat to 60°C)
DMSO : 1 mg/mL (7.40 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Onat F, et al. Antinociceptive effect of D-aspartic acid in mice. Pharmacology, biochemistry, and behavior. 1995 Aug;51(4):715-9. [Content Brief]
[2]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. Journal of neurochemistry. 1999 Sep;73(3):1206-11. [Content Brief]
[3]. Tong H, et al. Control over the crystal phase, shape, size and aggregation of calcium carbonate via a L-aspartic acid inducing process. Biomaterials. 2004 Aug;25(17):3923-9. [Content Brief]
[4]. MacDonald JF, et al. L-Aspartic acid induces a region of negative slope conductance in the current-voltage relationship of cultured spinal cord neurons. Brain research. 1982 Apr 08;237(1):248-53. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O / 1 M NaOH | 1 mM | 7.4025 mL | 37.0124 mL | 74.0247 mL | 185.0618 mL |
| 5 mM | 1.4805 mL | 7.4025 mL | 14.8049 mL | 37.0124 mL | |
| H2O / 1 M NaOH | 10 mM | 0.7402 mL | 3.7012 mL | 7.4025 mL | 18.5062 mL |
| 1 M NaOH | 15 mM | 0.4935 mL | 2.4675 mL | 4.9350 mL | 12.3375 mL |
| 20 mM | 0.3701 mL | 1.8506 mL | 3.7012 mL | 9.2531 mL | |
| 25 mM | 0.2961 mL | 1.4805 mL | 2.9610 mL | 7.4025 mL | |
| 30 mM | 0.2467 mL | 1.2337 mL | 2.4675 mL | 6.1687 mL | |
| 40 mM | 0.1851 mL | 0.9253 mL | 1.8506 mL | 4.6265 mL | |
| 50 mM | 0.1480 mL | 0.7402 mL | 1.4805 mL | 3.7012 mL | |
| 60 mM | 0.1234 mL | 0.6169 mL | 1.2337 mL | 3.0844 mL | |
| 80 mM | 0.0925 mL | 0.4627 mL | 0.9253 mL | 2.3133 mL | |
| 100 mM | 0.0740 mL | 0.3701 mL | 0.7402 mL | 1.8506 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Aspartic acid-1,4-13C2 Related Classifications
HY-N0666S6 Related Classifications
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