L-Aspartic acid-13C4,15N
Based on 1 Customer Validation
L-Aspartic acid-13C4,15N is the 15N, 13C-labeled L-Aspartic acid (HY-N0666). L-Aspartic acid is a NMDA receptor agonist and acidic amino acid. L-Aspartic acid has no independent analgesic activity. L-Aspartic acid can antagonize the analgesic effects of D-Aspartic acid and Morphine. L-Aspartic acid regulates polymorph transformation, crystal growth/aggregation and nucleation processes of calcium carbonate, and can serve as a biomineralization template. L-Aspartic acid promotes burst firing of central neurons. L-Aspartic acid can be used in studies related to cerebral ischemia and epilepsy.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 202468-27-7
- Formula: 13C4H7 15NO4
- Molecular Weight:138.07
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Storage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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NMDA Receptor |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 202468-27-7
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Unlabeled Cas 56-84-8
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Appearance Solid
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Molecular Weight 138.07
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Formula 13C4H7 15NO4
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Color White to off-white
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SMILES
O[13C]([13CH2][13C@H]([15NH2])[13C](O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvent & Solubility
1 M NaOH : 100 mg/mL (724.27 mM; ultrasonic and adjust pH to 12 with NaOH)
H2O : 2 mg/mL (14.49 mM; ultrasonic and warming and heat to 60°C)
DMSO : 1 mg/mL (7.24 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Onat F, et al. Antinociceptive effect of D-aspartic acid in mice. Pharmacology, biochemistry, and behavior. 1995 Aug;51(4):715-9. [Content Brief]
[2]. Hosoya K, et al. Blood-brain barrier produces significant efflux of L-aspartic acid but not D-aspartic acid: in vivo evidence using the brain efflux index method. Journal of neurochemistry. 1999 Sep;73(3):1206-11. [Content Brief]
[3]. Tong H, et al. Control over the crystal phase, shape, size and aggregation of calcium carbonate via a L-aspartic acid inducing process. Biomaterials. 2004 Aug;25(17):3923-9. [Content Brief]
[4]. MacDonald JF, et al. L-Aspartic acid induces a region of negative slope conductance in the current-voltage relationship of cultured spinal cord neurons. Brain research. 1982 Apr 08;237(1):248-53. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O / 1 M NaOH | 1 mM | 7.2427 mL | 36.2135 mL | 72.4270 mL | 181.0676 mL |
| 5 mM | 1.4485 mL | 7.2427 mL | 14.4854 mL | 36.2135 mL | |
| H2O / 1 M NaOH | 10 mM | 0.7243 mL | 3.6214 mL | 7.2427 mL | 18.1068 mL |
| 1 M NaOH | 15 mM | 0.4828 mL | 2.4142 mL | 4.8285 mL | 12.0712 mL |
| 20 mM | 0.3621 mL | 1.8107 mL | 3.6214 mL | 9.0534 mL | |
| 25 mM | 0.2897 mL | 1.4485 mL | 2.8971 mL | 7.2427 mL | |
| 30 mM | 0.2414 mL | 1.2071 mL | 2.4142 mL | 6.0356 mL | |
| 40 mM | 0.1811 mL | 0.9053 mL | 1.8107 mL | 4.5267 mL | |
| 50 mM | 0.1449 mL | 0.7243 mL | 1.4485 mL | 3.6214 mL | |
| 60 mM | 0.1207 mL | 0.6036 mL | 1.2071 mL | 3.0178 mL | |
| 80 mM | 0.0905 mL | 0.4527 mL | 0.9053 mL | 2.2633 mL | |
| 100 mM | 0.0724 mL | 0.3621 mL | 0.7243 mL | 1.8107 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
L-Aspartic acid-13C4,15N Related Classifications
HY-N0666S1 Related Classifications
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