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Results for "

Platycodon grandiflorum

" in MedChemExpress (MCE) Product Catalog:

19

Inhibitors & Agonists

18

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N3519
    Platycodin D3
    1 Publications Verification

    		 HCV Branched Chain Amino Acid Transaminase (BCAT) Interleukin Related NF-κB ERK p38 MAPK JNK Infection Inflammation/Immunology
    Platycodin D3 is a triterpenoid saponin that can be found in Platycodon grandiflorum. Platycodin D3 exhibits multiple activities including anti-inflammation, regulation of airway mucus secretion, improvement of asthmatic airway inflammation and remodeling, and inhibition of hepatitis C virus (HCV) replication. The IC50 value of Platycodin D3 against HCV NS5B RNA-dependent RNA polymerase is 8 μg/mL. Platycodin D3 can be used in studies related to asthma, hepatitis C virus infection and inflammatory diseases .
    Platycodin D3
  • HY-N4087
    Platycodin D2
    3 Publications Verification

    		 Mitophagy Autophagy Ferroptosis Interleukin Related IFNAR Reactive Oxygen Species (ROS) Inflammation/Immunology Cancer
    Platycodin D2 is an orally active triterpenoid saponin found in Platycodon grandiflorum. Platycodin D2 induces mitophagy in cancer cells through NIX, thereby activating the P21/CyclinA2 pathway and promoting cell senescence. Platycodin D2 induces mitochondrial dysfunction, enhances autophagy, inhibits hepatocellular carcinoma cell proliferation, and exhibits anti-tumor activity against multiple cancer cell types. Platycodin D2 promotes mRNA expression of T-bet, GATA-3, Th1 cytokines IL-2 and IFN-γ, and Th2 cytokines IL-4 and IL-10, enhances splenocyte proliferation, and acts as a vaccine adjuvant with low rabbit red blood cell hemolytic activity. Platycodin D2 induces mitochondrial ROS production, incomplete autophagy, and ferroptosis to inhibit breast cancer cell proliferation. Platycodin D2 can be used for the research of cancer, inflammation and immunology .
    Platycodin D2
  • HY-N3520
    Deapi-platycodin D3
    1 Publications Verification

    		 Others Metabolic Disease Inflammation/Immunology
    Deapi-platycodin D3 is a triterpenoid saponin from the roots of Platycodon grandiflorum .
    Deapi-platycodin D3
  • HY-N3521
    Platycoside G1

    Deapi-platycoside E

    		 Others Others
    Platycoside G1, a natural product found in Platycodon grandiflorum, is a triterpenoid saponin. Platycoside G1 has potent antioxidant activities .
    Platycoside G1
  • HY-N9377
    Platyconic acid A

    		Others Metabolic Disease Inflammation/Immunology
    Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation .
    Platyconic acid A
  • HY-N6064
    Polygalacin D
    3 Publications Verification

    		 Apoptosis IAP Cancer
    Polygalacin D (PGD) is a bioactive compound isolated from Platycodon grandiflorum with anticancer and anti-proliferative properties. PGD suppresses the expression of the IAP family of proteins including survivin, cIAP-1 and cIAP-2 and blocks the PI3K/Akt pathway by inhibiting the phosphorylation of GSK3β, Akt and the expression of PI3K. Polygalacin D induces apoptosis
    Polygalacin D
  • HY-N0588
    Deapioplatycodin D
    3 Publications Verification

    		 HCV Infection
    Deapioplatycodin D is a triterpenoid saponin isolated from Platycodon grandiflorum, with anti-HCV activity .
    Deapioplatycodin D
  • HY-N3522
    Platycoside E
    2 Publications Verification

    		 Others Inflammation/Immunology
    Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice .
    Platycoside E
  • HY-N8922
    Platycodin A

    		Others Others
    Platycodin A is monoacetylated saponin compound isolated fromhe roots of Platycodon grandiflorum A. DC. .
    Platycodin A
  • HY-N8810
    Platycoside M1

    		Others Others
    Platycoside M1 is a A-ring lactone triterpenoid saponin that can be isolaoted from the roots of Platycodon grandiflorum. Platycosides are the main active constituents of P. grandiflorus with multiple pharmacological activities .
    Platycoside M1
  • HY-125530
    Platycoside A

    		Others Others
    Platycoside A is a nature product. Platycoside A can be derived from Platycodon grandiflorum .
    Platycoside A
  • HY-N12587
    Platycoside F

    		Others Inflammation/Immunology
    Platycoside F is a triterpenoid saponin compound that can be isolated from the roots of Platycodon grandiflorum .
    Platycoside F
  • HY-N1991
    Platicodigenin

    		Others Others
    Platicodigenin isolated from platycodon grandiflorum.
    Platicodigenin
  • HY-N17333
    Platycoside D

    		Others Others
    Platycoside D is a triterpenoid saponin present in the roots of Platycodon grandiflorum .
    Platycoside D
  • HY-N10074
    Polygalacin D2

    		Others Others
    Polygalacin D2 is a saponin isolated from Platycodon grandiflorum .
    Polygalacin D2
  • HY-N8807
    Platycoside K

    		Others Others
    Platycoside K is a Triterpenoids product that can be isolated from the roots of Platycodon grandiflorum. .
    Platycoside K
  • HY-N8838
    Platycoside M3

    		Others Others
    Platycoside M3 is a Triterpenoids product that can be isolated from the roots of Platycodon grandiflorum. .
    Platycoside M3
  • HY-N3523
    3-O-Beta-D-Glucopyranosylplatycodigenin

    		Others Cancer
    3-O-Beta-D-Glucopyranosylplatycodigenin is an oleanane-type triterpenoid isolated from roots of Platycodon grandiflorum. 3-O-Beta-D-Glucopyranosylplatycodigenin exhibits anti-proliferative activities against HSC-T6 cell line with an IC50 of 13.36 μM .
    3-O-Beta-D-Glucopyranosylplatycodigenin
  • HY-N18092
    Platycodin C

    		Others Others
    Platycodin C is an oleanane-type oligoglycoside and monoacetylated saponin found in the roots of Platycodon grandiflorum A. DC. (Campanulaceae) .
    Platycodin C

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